BACKGROUND Atherosclerosis is the major cause of morbidities and mortalities worldwide. In this study we aimed to review the mechanism of atherosclerosis and its risk factors, focusing on new findings in atherosclerosis markers and its risk factors. Furthermore, the role of antioxidants and medicinal herbs in atherosclerosis and endothelial damage has been discussed and a list of important medi...

Perivascular adipose tissue (PVAT) and its adipokines engage in bidirectional crosstalk with the vascular wall. Atherosclerosis disrupts this interaction through inflammation, rupture-prone plaques, subsequent thrombosis. The cardioprotective effects of ghrelin are contradiction to adipogenic properties. concurrent research anti-/pro-atherogenic mechanisms PVAT-derived provides a better underst...

Background: Atherosclerosis is a main potential pathology of most cardiovascular diseases. Growing evidence has indicated that dysregulation ferroptosis associated with atherosclerosis. Dapagliflozinas sodiumglucose cotransporter 2 inhibitor (SGLT2i), in view the clinically important benefits sodium-glucose (SGLT2i) dapagliflozin improving outcomes, we aimed to explore its pharmacological effec...

Atherosclerosis is a chronic vascular disease that poses significant threat to human health. Common diagnostic methods mainly rely on active screening, which often misses the opportunity for early detection. To overcome this problem, paper presents novel medical ambient intelligence system detection of atherosclerosis by leveraging clinical data from records. The architecture includes extractio...

BACKGROUND We previously reported the arterial elasticity value we measured to reflect the characteristic features of vessel walls, and to possibly be useful for detecting early stage atherosclerosis in type 2 diabetes. Obesity, especially visceral adiposity, is well known to play a crucial role in the development of metabolic disorders and atherosclerosis. To assess whether arterial elasticity...

BACKGROUND Infection with Chlamydia pneumoniae has been postulated to play a pathogenic role in atherosclerosis. We examined the role of infection with C pneumoniae in relation to the extent of coronary atherosclerosis. METHODS AND RESULTS Coronary atherosclerosis was graded microscopically on a postmortem basis in a blinded fashion in 60 subjects as mild (n=18) or severe (n=42) atheroscleros...

Atherosclerosis developed in the arterial wall is major cause of cardiovascular events such as stroke and heart failure. Atherosclerosis, also referred to plaque can be classified stable, unstable, vulnerable plaque. In terms features compositions structures, atherosclerosis calcified plaque, with a lipid core, thin fibrous cap. It expected that compositions, mechanical properties plaques inter...

Background Periodontitis is a high prevalence disease, affecting up to 80% of the world's population. Recently studies have shown connection between periodontal disease and cardiovascular as oxidative stress plays an important role in chronic inflammatory diseases such disease. Nuclear factor erythroid 2 - related (Nrf2) core transcriptional regulator endogenous antioxidant system cellular defe...

Background and Aims : Cardiovascular disease, the leading cause of mortality worldwide, is primarily caused by atherosclerosis, which characterized lipid inflammatory cell accumulation in blood vessels carotid intima thickening, among others. Although disease management has improved significantly, new therapeutic strategies focused on accelerating atherosclerosis regression must be developed. A...