PURPOSE Some studies report a role of leukotrienes in the pathogenesis of atopic dermatitis and suggest a rationale for the use of leukotriene receptor antagonist (LTRA) in the treatment of atopic dermatitis. This study aimed to evaluate the treatment effectiveness of montelukast in children with atopic dermatitis. METHODS Fifty-four children between the ages of 2 and 6 years with moderate to...

Atopic dermatitis is the commonest skin disease in children, causing psychological, social and functional disability to them and their families. This study assessed the family impact and quality of life using the translated Malay version of The Dermatology Family Impact (DFI) and The Children's Dermatology Life Quality Index (CDLQI) questionnaires. Seventy-two children, aged between 6 months an...

BACKGROUND Atopic dermatitis constitutes a most burdensome chronic inflammatory skin disease. Standard treatment is cumbersome and often targets its main symptom, pruritus, only insufficiently. FINDINGS Recent advances in our understanding of the role of histamine and its four receptors suggest new approaches which target the histamine receptors alone or as combination therapies to more effic...

Colloidal oatmeal has been used for decades to soothe and ameliorate atopic dermatitis and other pruritic and/or xerotic dermatoses. In-vitro and/or in-vivo studies have confirmed the anti-inflammatory, barrier repair, and moisturizing properties of this compound. A broad set of studies has been conducted in recent years to assess the effects of colloidal oatmeal as adjunct treatment in the man...

338 Early Clinical Differential Diagnosis between Infant Atopic Dermatitis and Seborrheic Eczema Rubens Marcelo Souza Leite, MD, and Adriana Aragao Craveiro Leite, MD. Departamento Medico, Camara dos Deputados, Brasilia, Brazil; Allergy, Instituto Saint Louis, Brasilia, Brazil. Background: Clinical differential diagnosis between atopic dermatitis and seborrheic eczema is sometimes difficult. Ea...

Little is known about the classification and bacterial infection in outpatients with eczema and dermatitis in China.To investigate the prevalence of eczema and dermatitis in outpatients of dermatology clinics in China, examine classification and proportion of common types of dermatitis and the possible bacterial infection, and analyze the possible related factors.Outpatients with eczema or derm...

3. Jekler J, LarkoÈ O. Combined UVA-UVB versus UVB photo7. Hudson-Peacock MJ, DiŒey BL, Farr PM. Narrow-band UVB phototherapy for severe atopic dermatitis. Br J Dermatol 1996; therapy for atopic dermatitis: a paired comparison study. J Am Acad Dermatol 1990; 22: 49± 53. 135: 332. 8. Grundmann-Kollman M, Behrens S, Podda M, Peter RU, 4. El-Ghorr AA, Norval M. Biological eŒects of narrow-band (31...

Our objective was to evaluate the relationship between intrauterine exposure to cadmium and the presence of atopic dermatitis in infants 6 months of age, adjusted for covariates including exposure to other heavy metals. The present research is a component of the Mothers' and Children's Environmental Health (MOCEH) study, a multi-center birth cohort project conducted in Korea. Study subjects wer...

BACKGROUND The relationships between cockroach and mouse allergen exposure, anti-cockroach and anti-mouse IgE, and wheeze, rhinitis, and atopic dermatitis in children as young as age 3 years are of public health importance but have not been thoroughly evaluated. OBJECTIVE We hypothesized that inner-city children might have anti-cockroach and anti-mouse IgE by age 3 years, and their presence w...

Dendritic hPG-amid-C18-mPEG core-multishell nanocarriers (CMS) represent a novel class of unimolecular micelles that hold great potential as drug transporters, e.g., to facilitate topical therapy in skin diseases. Atopic dermatitis is among the most common inflammatory skin disorders with complex barrier alterations which may affect the efficacy of topical treatment.Here, we tested the penetrat...