نتایج جستجو برای: atria fibrillation

تعداد نتایج: 62691  

Journal: :Circulation 1993
J Wang G W Bourne Z Wang C Villemaire M Talajic S Nattel

BACKGROUND Antiarrhythmic drugs are considered to terminate atrial fibrillation by prolonging refractoriness, but direct experimental evaluation of this concept has been limited. The atria are activated rapidly during atrial fibrillation, and antiarrhythmic drugs are known to have important rate-dependent actions. The potential role of such properties in determining drug effects during atrial f...

Journal: :Circulation 2013
Brian O Bingen Zeinab Neshati Saïd F A Askar Ivan V Kazbanov Dirk L Ypey Alexander V Panfilov Martin J Schalij Antoine A F de Vries Daniël A Pijnappels

BACKGROUND Atrial fibrillation is the most common cardiac arrhythmia. Ventricular proarrhythmia hinders pharmacological atrial fibrillation treatment. Modulation of atrium-specific Kir3.x channels, which generate a constitutively active current (I(K,ACh-c)) after atrial remodeling, might circumvent this problem. However, it is unknown whether and how I(K,ACh-c) contributes to atrial fibrillatio...

Journal: :Acta Cardiologica Sinica 2014
Chien-Jung Chang Ten-Fang Yang Tin-I Lee Yao-Chang Chen Yu-Hsun Kao Shih-Ann Chen Yi-Jen Chen

BACKGROUND The pulmonary veins (PVs) and atria are important foci during that period when atrial fibrillation (AF) is generated and maintained. It is well understood that hypertension and diabetes mellitus (DM) are important risk factors for AF. Dipeptidyl peptidase-IV (DPP-4) inhibitors are new agents in the fight against type 2 DM, though they have been found to have several cardiovascular ef...

Journal: :Cardiovascular research 2013
Marta González de la Fuente Adriana Barana Ricardo Gómez Irene Amorós Pablo Dolz-Gaitón Sandra Sacristán Felipe Atienza Ana Pita Ángel Pinto Francisco Fernández-Avilés Ricardo Caballero Juan Tamargo Eva Delpón

AIMS β-adrenergic stimulation has profound influence in the genesis and maintenance of atrial fibrillation (AF). However, the effects of β-Adrenoceptor stimulation on repolarizing currents and action potential (AP) characteristics in human atrial myocytes from left (LAA) and right atrial appendages (RAA) obtained from sinus rhythm (SR) and chronic atrial fibrillation (CAF) patients have not bee...

Journal: :Circulation 1999
T O Cheng

To the Editor: I read with interest the article on the treatment of patients who have sick sinus syndrome (SSS) with single-chamber atrial pacing by Anderson et al.1 However, their finding of the annual risk of secondor third-degree atrioventricular (AV) block of only 0.6% per year contrasts somewhat with the reported findings that abnormal AV conduction was demonstrated in 57% to 67% of patien...

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