We present a case of left atrial appendage (LAA) aneurysm and atrial septal defect in a 1-year-old child without cardiovascular symptoms referred for cardiac murmurs and cardiomegaly and diagnosed by 2and 3-dimensional transthoracic echocardiography. Subcostal and apical views showed a wide, fenestrated ostium secundum-type atrial septal defect with redundant septum (Fig. 1, arrow). The right-s...

IN CONTRAST to cases of ventricular septal defect in which pulmonary arterial lesions occur at a very early age, such changes are generally considered to be late phenomena in atrial septal defect. It is well known that pulmonary hypertension, when it occurs as a complication of a defect in the atrial septum, is usually not seen before adult life.1' 2 The pulmonary arteries are reported to be la...

It was possible to calculate pressure gradients across the interatrial septum in several cases of congenital heart disease. Gradients in cases of interatrial septal defect are similar to those found in animals with artificially produced defects. The data are used to form a rounded picture of the hemodynamics of interatrial septal defect. In pulmonic stenosis with interatrial communication, reve...

We previously reported on two male sibs with an unknown syndrome which included microcephaly, seizures, mental retardation, congenital heart disease, and skeletal abnormalities.' The subsequent clinical course and necropsy findings of one of the boys (sib 2) contribute substantial information to the original report. At 15 months of age he had findings of a large atrial septal defect with signif...

Afibrinogenemia or hypofibrinogenemia is a quantitative defect in fibrinogen. It is a rare disease with estimated frequency of 1 in 1,000,000 population. Routine preoperative screening tests of coagulation disorders are insufficient to detect subtle disorders of fibrinogen. Herein, we report a child who was supposed to undergo open cardiac surgery for a large atrial septal defect. Preoperative ...

Atrial septal defect (ASD) is second common congenital heart disease that often leads to adult period. Intracardiac or transesophageal echocardiography (TEE) is essential for percutaneous closure of ASD using Amplatzer septal occluder. Dexmedetomidine (DEX), which is a highly selective α2-agonist, has sedative and analgesic properties without respiratory depression in the clinical dose range. W...

L acerations or tears of the interatrial septum are a recognized complication of mitral valve replacement surgery; however, the first report of iatrogenic Lutembacher's syndrome was by Dr. John Ross Jr. and colleagues from the National Institutes of Health.1 Their series included three patients who had acquired mitral stenosis and developed a persistent atrial septal defect after transatrial se...

The inferior vena cava (IVC) is a rare site of focal atrial tachycardia (AT). Here, we report a 20-year-old woman who underwent catheter ablation for anti-arrhythmic drug-resistant AT originating from the IVC. She had undergone open-heart surgery for patch closure of an atrial septal defect 17 years previously and permanent pacemaker implantation for sinus node dysfunction 6 years previously. T...

ume overload was created in open-chest dogs by pumping blood from the left atrium to the right atrium. In seven of eight dogs changes in interventricular septum motion were produced acutely at shunt flow as low as 500 cc/min. When the shunt was decreased or stopped, interventricular septum motion returned to normal. Shunts producing left ventricular volume overload (aorta to left atrium and rig...

The article describes a successful clinical outcome in the case of 5-month old female with diagnosis incomplete vascular ring aberrant right subclavian artery and ostium secundum atrial septal defect associated partial anomalous pulmonary venous return scimitar syndrome type, coexisting sequestration. During hospitalization, surgical correction heart resection lung sequestration were performed....