MORISSET, JEAN, AND PAUL D. WEBSTER. Effects of atropine an pigeon pancreas. Am. J. Physiol. 219(5): 12864291. 1970.Cholinergic drug administration to pigeons was associated within 5 min with increased amylase secretion, increased uridine-3H incorporation into nucIear RNA, and increased L-phenylalaniner4C incorporation into amylase. The studies presented examine control and integration of pancr...

BACKGROUND Atropine reduces the rate of reflux episodes in normal subjects by inhibition of transient lower oesophageal sphincter (LOS) relaxations. The aim of this study was to investigate the effect of atropine on the rate and mechanisms of reflux in patients with reflux disease. METHODS Oesophageal motility and pH were recorded for one hour after a meal in 15 patients with reflux disease. ...

Previous tests on the use of large doses of atropine for the treatment of anticholinesterase poisoning have revealed postural hypotension following the administration of 2 mg. of this drug. In this study on 78 normal adult males, the cardiovascular responses to positional change after 2 mg. atropine have been measured and the mechanisms elucidated. Blood pressure response to tilting was normal ...

OF THE 600,000 people who die each year in the United States from acute myocardial infarction, approximately two thirds die prior to receiving medical attention.1-3 On the basis of data gathered by mobile coronary care units, it appears that most of these deaths result from ventricular fibrillation.4 Clearly, then, any intervention that can successfully modify or eliminate those factors which p...

In medical practice atropine sulphate is relied upon to relieve the acute pain caused by spasmodic contractions of involuntary muscle, such as occur in renal and intestinal colic. The acute pain of strangulated hernia is also due?in the majority of cases?to spasm of involuntary muscle of-the strangulated coils of intestine. If the spasm is relieved, reduction of the hernia may be much easier. W...

Objective: A retrospective study was conducted in a tertiary care hospital collaborated with medical college, to analyze the drug therapy including antidotes administered and pattern of Organophosphorous compounds poisoning. Material methods: The data are analytically drawn from record sheets poisoning patients. collected tabulated were statistically analyzed SPSS version for Results: demograph...

REASONS FOR PERFORMING STUDY Imidocarb dipropionate is the drug of choice for equine piroplasmosis but its administration causes severe colic and diarrhoea. An imidocarb protocol that reduces these effects is needed. OBJECTIVES 1) Quantification of the effects of imidocarb dipropionate on equine orocaecal transit time (OCTT), with and without atropine or glycopyrrolate premedication and 2) in...

Dose-response relationships of the cholinergic antagonist, atropine methonitrate, and the beta-adrenergic agonist, salbutamol, were examined by cumulative dose techniques. A wet aerosol, 1.5 mg atropine methonitrate produced a maximum response. The response to 200 microgram of salbutamol from a pressurised aerosol was close to maximum. Secondly, the bronchodilator response of salbutamol microgr...

men. Methods and Results. Responses to two 5-minute intravenous isoproterenol infusions (0.01 ug/kg/min and 0.02 pg/kg/min) were evaluated in six type A and six type B men after pretreatment with either dextrose placebo or atropine (1.2 mg). Atropine significantly potentiated T wave attenuation in the recovery period after isoproterenol infusion (0.30±0.07 mV) compared with placebo (0.54±0.09 m...

BACKGROUND Although dobutamine stress echocardiography (DSE) is performed in heart transplant patients, the safety profile of atropine administration in DSE in this setting is unclear. METHODS AND RESULTS We identified heart transplant patients who received atropine during DSE from January 1984 to August 2011 at our institution and compared them with a propensity-scored matched control group ...