auditory brainstem responses

نتایج جستجو برای: auditory brainstem responses

تعداد نتایج: 469812 فیلتر نتایج به سال:

α2δ3 is essential for normal structure and function of auditory nerve synapses and is a novel candidate for auditory processing disorders.

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2014

Antonella Pirone Simone Kurt Annalisa Zuccotti Lukas Rüttiger Peter Pilz David H Brown Christoph Franz Michaela Schweizer Marco B Rust Rudolf Rübsamen Eckhard Friauf Marlies Knipper Jutta Engel

The auxiliary subunit α2δ3 modulates the expression and function of voltage-gated calcium channels. Here we show that α2δ3 mRNA is expressed in spiral ganglion neurons and auditory brainstem nuclei and that the protein is required for normal acoustic responses. Genetic deletion of α2δ3 led to impaired auditory processing, with reduced acoustic startle and distorted auditory brainstem responses....

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α2δ3 is essential for normal structure and function of auditory nerve synapses and is a novel candidate for auditory processing disorders.

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