Abstract   Background: Hepatitis B virus infection is an important cause of liver morbidity and   mortality worldwide. HDV changes the natural course of HBV. The prevalence of HDV infection wasn’t determined in the various groups of HBV infection (carriers, acute hepatitis, chronic hepatitis, cirrhosis and HCC) in Iran. We aimed to research the prevalence of hepatitis D virus infection in v...

Autoimmune hepatitis also known as Lupoid hepatitis is an autoimmune liver disease characterized by the presence of autoantibodies including antinuclear antibodies (ANA) and hyper gammaglobulinemia. SLE can be associated with hepatitis, which is referred to as lupus hepatitis. It is important to distinguish these two entities, as the course of the disease is different in both. It has also been ...

methods fifty-three patients who were treated at the department of gastroenterology and hepatology of the university clinic essen from 2008 to 2013 included in this retrospective study. laboratory parameters were used to calculate non-invasive markers for liver fiibrosis. every patient underwent a liver biopsy within 6 months of the liver stiffness measurement. objectives autoimmune hepatitis (...

Background: Chronic liver diseases whatever their etiologies could be associated with immunological disturbances. Objectives: Our aim was to evaluate the prevalence and characteristics of autoimmune chronic diseases. Methods: We performed a retrospective analysis data from consecutive patients followed in our department for recruited January 2010 December 2019. Demographic, clinical, paraclinic...

The purpose of this investigation was to determine the role of alcohol in development of progressive liver disease. For this purpose, 41 alcoholic patients were followed up for 5 years. Criteria for alcohol abuse was that the patients were enjoying 20 g alcohol daily in a period of 5 years for females and respectively 60 g daily for males. In the same time a group of 51 nonalcoholic patients wi...

Sera from the patients with chronic liver diseases and hepatocellular carcinoma (HCC) were tested for reactivity with neutral glycosphingolipids extracted from rabbit liver plasma membrane by enzyme-linked immunosorbent assay and thin-layer chromatography immunostaining. IgG class antibody to neutral glycosphingolipids was detected in 29.6% (8 of 27), 6.3% (1 of 16), 0% (0 of 8), 0% (0 of 25), ...

BACKGROUND Hematopoietic stem cell transplantation (HSCT) remains the only curative treatment for many nonmalignant disorders, such as autoimmune disorders, inborn metabolic disorders, hemoglobinopathies, and immunodeficiency disorders. Autoimmune complications (AICs) after HSCT, such as autoimmune cytopenias, autoimmune hepatitis, primary biliary cirrhosis, and autoimmune cutaneous manifestati...

Interferon alpha is a molecule frequently used in the treatment of chronic hepatitis B, C, and D, with immunomodulatory and antiviral activity. It is also used in some cancer types. It has been widely claimed that interferon alpha triggers autoimmunity, with its broad adverse effect profile. Here we present the case of a 29-year-old male patient with chronic hepatitis B diagnosis who developed ...