BACKGROUND Autoimmune hepatitis (AIH) is a chronic inflammatory disease of the liver with nonspecific clinical manifestations that causes greater liver damage in children than in adults. AIMS To analyze the clinical progression, biochemical profiles, histopathologic changes, and treatment response in 20 children with AIH. MATERIAL AND METHODS A retrospective study was carried out on the var...

autoimmune polyglandular syndrome (aps) type 2 is characterized by the presence of addison's disease, in association with autoimmune thyroid disease and/or type 1 diabetes mellitus. aps type 2 occurs most often in middle aged females and is rare in children. here an 11 year old boy is reported with addison's disease who developed symptom's of diabetes mellitus, goiter, malabsorption, macrocytic...

BACKGROUND The occurrence in the same patient of three or more autoimmune diseases defines multiple autoimmune syndrome (MAS). Various autoimmune dermatoses, especially pemphigus, have been described in association with systemic autoimmune diseases as component of MAS. AIM The aim of our study is to describe MAS with a new combination in a 55-year-old woman having a pemphigus vulgaris, associ...