We monitored the behavior of residual myeloma plasma cells in patients with multiple myeloma after high-dose therapy and autologous or allogeneic transplantation using 3 methods of a flow cytometric technique using 4-color staining, immunofixation, and polymerase chain reaction approaches. We analyzed 17 cases by a relatively simple flow cytometric technique using CD38/CD45/CD19/CD56. Detectabl...

In most people, COVID-19 presents as a mild disease. However, in many especially those with comorbidities, profound inflammation manifesting cytokine storm may lead to acute respiratory distress syndrome and multi-organ failure. This novel study reports two severe patients from Koja Regional Hospital: male aged 52 female 65. Both had poor prognoses based on prognostic biomarkers, disseminated i...

In vitro interactions of purified lipoprotein lipase with plasma from type IV hyperlipidemic and normolipidemic subjects were studied using an automated cholesterol analysis adaptation to single vertical spin centrifugation. Lipolysis for 60 min of normolipidemic plasma (control) supplemented with autologous very low density lipoprotein (VLDL) resulted in a progressive conversion of VLDL to low...

The idiotype protein, secreted by myeloma plasma cells, is a tumor-specific but weak antigen. Idiotype-based immunotherapy has been explored in myeloma patients with disappointing results. It is conceivable that myeloma cells contain a multitude of tumor antigens that can more effectively stimulate antitumor T cells. To explore the possibility of using whole myeloma cells as a source of tumor a...

The management of severe recalcitrant atopic dermatitis (AD) is a challenging issue for clinicians and patients. We hypothesized that repeated intramuscular injections of autologous immunoglobulin (autologous immunoglobulin therapy: AIGT) might induce clinical improvements in patients with AD by stimulation of the active immune response to antigen-binding-site of pathogenic antibodies. We tried...

Platelet Rich Plasma contains a major Growth factor and has adhesive healing properties. PRP promotes angiogenesis, collagen synthesis, wound healing. The main aim of this study is to compare the efficacy SSG fixation using autologous platelet-rich plasma with conventional method like suturing. In study, patients who were admitted diagnosis ”ulcer” in General Surgery department SRM medical coll...

Background: Premature ovarian aging as evidenced by AMH levels less than 0.5 ng/ml is predictive of reduced success in management infertility. The most effective treatment vitro fertilization which not affordable or acceptable to our patients with low socioeconomic background. Intra-ovarian injection autologous platelet rich plasma (PRP) improves the reserve markers but it remains be seen wheth...

We assessed the effectiveness of the different treatments for plantar fasciitis (PF) based on the changes in functional outcomes. A systematic literature search was carried out and studies from 2010 to 2016 were included in this review. The databases from Google Scholar, PubMed and Cochrane were used for the various treatment modalities of plantar fasciitis. The objectives measured included vis...

Posttransfusion purpura typically occurs in PLA1 negative blood recipients who have been previously immunized to the PLA1 antigen. Following transfusion, severe thrombocytopenia develops with the formation of anti-PLA1. Since the patients' platelets lack the PLA1 antigen, one would not expect this antibody to destroy autologous platelets. In this study we show that PLA1 antigen exists in stored...

background tennis elbow (te) is a common myotendinosis. it was first described by runge in 1873; different modes of treatment are used in management of te. objectives this study aimed to report the results of autologous blood injection (abi) in the treatment of te. materials and methods a prospective case study was performed to evaluate the results of abi in the management of te. the level of p...