Assuming the nonavailability of some observations and the availability of some stochastic linear constraints connecting the coe cients in a linear regression the technique of mixed regression estimation is considered and a set of ve unbiased estimators for the vector of coe ceints is presented They are compared with respect to the criterion of variance covariance matrix and conditions are obtai...

SUMMARY PopHist is a computer program that uses the frequency spectrum of alleles to: (a) estimate maximum likelihood parameters describing a population's history; and (b) compare alternative hypotheses about population history using likelihood ratio tests. The program uses the matrix coalescent, a method for calculating theoretical frequency spectra that can be applied to sets of unlinked site...

A recent paper in Cell (Yao et al., 2006) and two papers in Developmental Cell (Tenzen et al., 2006; Zhang et al., 2006) identify a new receptor component for Hedgehog, a key morphogen in embryonic development. Many other proteins that bind to Hedgehog in the extracellular matrix or on the cell surface have been identified. In light of these recent discoveries, we discuss how these factors cont...

Stationary electric transport in semiconductor nanostructures is studied by the method of nonequilibrium Green functions. In the case of sequential tunneling the results are compared with density matrix theory, providing almost identical results. Nevertheless, the method of Green functions is easier to handle due to the availability of an absolute energy scale. It is demonstrated, that the tran...

SUMMARY VistaClara is a plug-in for Cytoscape which provides a more flexible means to visualize gene and protein expression within a network context. An extended attribute browser is provided in the form of a graphical and interactive permutation matrix that resembles the heat map displays popular in gene-expression analysis. This extended browser permits a variety of display options and intera...

This paper surveys the recent developments in the area of equalization of the wireless propagation channels. It focuses on a subclass of equalization algorithms that minimizes the Mean Square Error (MMSE) between the desired and estimated signal. The following aspects of the equalization problem are considered: system modeling, algorithm classification based on the availability of training sequ...

In this paper we work with the filtering problem for a special class of discrete-time Markov Jump Linear Systems (MJLS) whose transition probability matrix has identical rows. For that class of systems we design, with the help of new necessary and sufficient LMI conditions, H2 optimal modeindependent filters with the same order of the plant. For cluster availability of the mode, we also show it...

UNLABELLED We present and review coupled two-way clustering, a method designed to mine gene expression data. The method identifies submatrices of the total expression matrix, whose clustering analysis reveals partitions of samples (and genes) into biologically relevant classes. We demonstrate, on data from colon and breast cancer, that we are able to identify partitions that elude standard clus...

Chronic wounds fail to progress through the main phases associated with normal wound healing. One of the main suggestions for this is they become trapped in a chronic inflammatory state (Ennis and Meneses, 2000). Dysfunction at a cellular level has been associated with this, including problems in the modulation of matrix metalloproteinases (MMPs) and the availability of growth factors (Trengrov...