نتایج جستجو برای: based view rbv

تعداد نتایج: 3119149  

2003
Tom Butler Ciaran Murphy

The process by which IT competencies are created and applied to develop firm specific IT resources is not well understood. Previous research on the phenomenon has operated from the resource-based view (RBV); however, conceptual problems with resource-based theory have neither been noted nor addressed by IS researchers. This study acknowledges these problems and provides a solid conceptual found...

Journal: :Informatica (Slovenia) 2011
Pedro Soto-Acosta Ricardo Colomo Palacios Daniel Perez González

The resource-based view (RBV) ascribes superior firm performance to firm resources and capabilities. In recent years, much debate about the value of e-business has been raised because of the costly investments required. Although studies have found positive relationships between e-business and firm performance, there is a need to further investigate into these topics. Since innovation has become...

2017
Hugo Perazzo Marcelino Jose Jorge Julio Castro Silva Alexandre Monken Avellar Patrícia Santos Silva Carmen Romero Valdilea Gonçalves Veloso Ruben Mujica-Mota Rob Anderson Chris Hyde Rodolfo Castro

BACKGROUND Eradication of hepatitis C virus (HCV) using direct-acting agents (DAA) has been associated with a financial burden to health authorities worldwide. We aimed to evaluate the guideline-based treatment costs by DAAs from the perspective of the Brazilian Ministry of Health (BMoH). METHODS The activity based costing method was used to estimate the cost for monitoring/treatment of genot...

Journal: :Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2006
John Hornberger Francesca J Torriani Douglas T Dieterich Norbert Bräu Mark S Sulkowski Maribel Rodriguez Torres Jesse Green Kavita Patel

BACKGROUND A multinational trial (APRICOT) showed that peginterferon alfa-2a (40kDa) plus ribavirin is efficacious for treatment of HIV-HCV co-infection. The cost-effectiveness of treating these patients with peginterferon alfa-2a/ribavirin has yet to be explored from a US societal perspective. OBJECTIVE To predict the cost-effectiveness of peginterferon alfa-2a/ribavirin with interferon/riba...

2015
Antonio Navarro-García Jorge Arenas-Gaitán Javier Rondán-Cataluña

This research has two main objectives. Firstly, this research contributes to defining the concept of export entrepreneurship from a theoretical point of view, and this is a contribution taking into account the scarce and fragmented literature published about this topic. Furthermore, the authors explain export entrepreneurship dimensions – speed, degree, and scope. Thirdly, we empirically analyz...

2015
Raoel Maan Adriaan J. van der Meer Willem Pieter Brouwer Elisabeth P. C. Plompen Milan J. Sonneveld Robert Roomer Annemiek A. van der Eijk Zwier M. A. Groothuismink Bettina E. Hansen Bart J. Veldt Harry L. A. Janssen Andre Boonstra Robert J. de Knegt Chen-Hua Liu

BACKGROUND/OBJECTIVE Genetic polymorphisms in the inosine triphosphatase (ITPA) gene have been associated with the protection from early ribavirin(RBV)-induced hemolytic anemia among patients with chronic hepatitis C virus (HCV) infection. The aim of the present study was to investigate the association between the functional ITPA variants and hematological side effects during antiviral therapy ...

Journal: :Hepatology 2011
Alexander J Thompson Rosanna Santoro Valeria Piazzolla Paul J Clark Susanna Naggie Hans L Tillmann Keyur Patel Andrew J Muir Kevin V Shianna Leonardo Mottola Daniela Petruzzellis Mario Romano Fernando Sogari Domenico Facciorusso David B Goldstein John G McHutchison Alessandra Mangia

UNLABELLED Two functional variants in the inosine triphosphatase (ITPA) gene causing inosine triphosphatase (ITPase) deficiency protect against ribavirin (RBV)-induced hemolytic anemia and the need for RBV dose reduction in patients with genotype 1 hepatitis C virus (HCV). No data are available for genotype 2/3 HCV. We evaluated the association between the casual ITPA variants and on-treatment ...

Journal: :Procedia Computer Science 2022

Industry 4.0 technologies and technological concepts can be considered as a starting point to strengthen the long-term competitiveness of modern enterprises. In this context, only handful recent studies consider importance professional 4.0-driven servitization and, therefore, investigate causal relationship between company performance. This paper aims preliminary scrutinize set influencing fact...

2014
Partha K. Chandra Feyza Gunduz Sidhartha Hazari Ramazan Kurt Rajesh Panigrahi Bret Poat David Bruce Ari J. Cohen Humberto E. Behorquez Ian Carmody George Loss Luis A. Balart Tong Wu Srikanta Dash Ranjit Ray

PURPOSE Chronic Hepatitis C Virus (HCV)-infected patients with liver cirrhosis (LC) respond poorly to interferon-alpha (IFN-α) and ribavirin (RBV) combination therapy, but the reason for this is unclear. We previously reported that HCV-infection induces endoplasmic reticulum (ER) stress and autophagy response that selectively down regulates the type I IFN-α receptor-1 (IFNAR1) and RBV transport...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012
Benjamin P Linas Angela Y Wong Bruce R Schackman Arthur Y Kim Kenneth A Freedberg

BACKGROUND We used a Monte Carlo computer simulation to estimate the effectiveness and cost-effectiveness of screening for acute hepatitis C virus (HCV) infection in human immunodeficiency virus (HIV)-infected men who have sex with men. METHODS One-time screening for prevalent HCV infection was performed at the time of enrollment in care, followed by either symptom-based screening, screening ...

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