protein tyrosine phosphatases (ptpases) regulate the tyrosine phosphorylation of target proteins in volved in several biological activities including cell proliferation and transformation. protein tyrosine phosphatase e (ptpe) contains duplicated ptpase-like domains and a short extracellular region. us ing the fluorescence in situ hybridization method, the gene encoding ptpe (locus symbol ptpre...

Drimia is a heterogeneous, poorly understood genus that requires major rearrangement. Chromosome behavior of gigantea and viridula; two species in D. altissima complex was studied for karyotypes transmission extra chromosomes pair pollen viability. Meristematic cells at the root tips viridula were by conventional cytogenetic karyotype analysis. numbers 2n = 22 20 viridula, respectively. Extra c...

The cytogenetic hallmark of Chronic Myeloid Leukemia (CML) is the presence Philadelphia (Ph) chromosome, which results from a reciprocal translocation t(9;22)(q34;q11). In this report, we describe CML patient with no evidence Ph chromosome but trisomy 8 as single abnormality and typical e14a2 (b3a2) BCR-ABL1 fusion transcript. Fluorescence Situ Hybridization (FISH) analysis revealed an uncommon...

The karyotype is a basic concept regarding the genome, fundamentally described by the number and morphological features of all chromosomes. Chromosome class, centromeric index, intra- and interchromosomal asymmetry index, and constriction localization are important in clinical, systematic and evolutionary approaches. In spite of the advances in karyotype characterization made over the last year...

We investigated if any change in spatial resolution of comparative genomic hybridization analysis could be detected when using DNA amplified by degenerate oligonucleotide primed PCR (DOP-PCR) as opposed to the use of unamplified DNA. Five DNA samples from B-cell leukemias with small 11q deletions were amplified by DOP-PCR and analysed by means of high resolution comparative genomic hybridizatio...

Original meiotic or mitotic chromosome counts are presented for 17 species in 12 families of angiosperms from Iran. Chromosome counts for Amberboa nana, n=16 (Asteraceae) and Camelina rumelica subsp. transcapica, n=13 (Brassicaceae) are repoted for the first time. Chromosome numbers for six species including: Rhagadiolus stellatus (n=5), Campanula raponcoloides (n=34), Campanula trachelium (n=1...

We are reporting a case of 47 chromosome complement with an extra rearranged chromosome 22pter→22qll:: llq23 → llqter in a child with multiple malformations whose mother has a balanced reciprocal translocation t(1l,22) with a history of two previous abortions. We emphasize the importance of family study in such cases.

in this syudy a continuous bovine kidney cell line derived from a primary bovine kidney cells was established for the first time in iran. the cells were originating from two-day-old normal male calf of holstein breed. the cell cultures were continuously passaged following complete proliferation of primary cells. the specific properties or characteristics of the cell were defined using cytogene...

Picture the scene. Neurologist on the telephone to a Departmental Librarian on a Friday morning. The last 5 years have seen a major transformation in neurology, particularly in the understanding of those disorders where inheritance is either auto-somal dominant, recessive or X-linked. Collaboration between Departments of Molecular Genetics and Neurology has developed to a point where gene marke...