Neonatal suppressor T cells were isolated from the thymuses of 10- to 14-day old BDF mice infected at birth with mouse thymic virus. Such cells were enriched for suppressive activity directed against antibody formation by adult B cells and represented a relatively homogenous population of outer cortical cells. Their surface antigen phenotype was found to be: Ly 1+, Ly 2+, TL+, Thy 1+, and H-2+....

In this work we deal with the numerical solution of the fluid-structure interaction problem arising in the haemodynamic environment. In particular, we consider BDF and Newmark time discretization schemes, and we study different methods for the treatment of the fluid-structure interface position, focusing on partitioned algorithms for the prescription of the continuity conditions at the fluid-st...

In solving stiff systems of ordinary differential equations using BDF methods, Jacobians needed for quasi-Newton iteration are frequently computed using finite differences. Round-off errors in the finite-difference approximation can lead to Newton failures forcing the code to choose its time steps based on “stability” rather than accuracy considerations. When standard stepsize control is used, ...

Implicit-explicit (IMEX) multistep methods are very useful for the time discretiza-tion of convection diffusion PDE problems such as the Burgers equations and also the incompressible Navier-Stokes equations. Semi-discretization in space of the latter typically gives rise to an index 2 differential-algebraic (DAE) system of equations. Runge-Kutta (RK) methods have been considered for the time di...

Review scope Included studies compared combined ICS plus LABA (ICS/LABA) inhalers (fluticasone and salmeterol [FPS] or budesonide and formoterol [BDF]) with the same LABA alone in adults > 40 years of age who had stable COPD and had not had an exacerbation in the past month. Studies of patients who had partial reversibility on pulmonary function testing were included. Studies that included pati...