Pentacyclic triterpenes are secondary plant metabolites widespread in fruit peel, leaves and stem bark. In particular the lupane-, oleanane-, and ursane triterpenes display various pharmacological effects while being devoid of prominent toxicity. Therefore, these triterpenes are promising leading compounds for the development of new multi-targeting bioactive agents. Screening of 39 plant materi...

The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separation of the extracts lead to isolation of two new xanthones, identified as nodusuxanthone and trap...

The phytochemical content (total phenolic compounds, total flavonoids, condensed tannins and phenolic composition) and the antioxidant potential of Rhus tripartitum fruits collected from different localities were screened during maturity. Significant variability was detected. HPLC analyses revealed the presence of 24 compounds with notable differences. Flavone and betulinic acid, which have num...

In addition to benjaminamide (2), β-amyrin, β-amyrin acetate, lupeol, betulinic acid, β-sitosterol glucoside, a new ceramide glycoside was isolated from the woods of Ficus lutea Vahl (Moraceae). Using mass fragmentation pattern, 1 and 2D NMR spectra and by comparison with published data, the new compound was characterized as 1-O-β-D-glucopyranosyl-(2S,3R,5E,12E)-2N-[(2'R)-hydroxyhexadecanoyl]-o...

Herein, we report the occurrence of four new compounds in ethanolic extract Albizia coriaria Welw ex. Oliver leaves along with other previously reported this species. The were isolated and characterized using column chromatography, Fourier Transform Infrared (FTIR) gas chromatography/mass spectrometry. FTIR spectrum showed phenolic OH stretching (3362.30 cm-1), C=O (1660.08 CO (1369.46 cm-1 131...

The treatment of cancer with chemotherapeutic agents and radiation has two major problems: time-dependent development of tumor resistance to therapy (chemoresistance and radioresistance) and nonspecific toxicity toward normal cells. Many plant-derived polyphenols have been studied intently for their potential chemopreventive properties and are pharmacologically safe. These compounds include gen...