Multiple endocrine neoplasia type 2 (MEN2) is a autosomal dominat inherited tumour-syndrome caused by germline activating mutations of the RET proto-oncogene on chromosome 10. It is clinically characterized by the presence of medullary thyroid carcinoma (MTC), bilateral pheochromocytoma and primary hyperparathyroidism (MEN2A) within a single patient. Three distinct clinical forms have been desc...

BACKGROUND Surgical difficulty in laparoscopic adrenalectomy for pheochromocytoma increases with tumor size. We compared single surgeon outcomes of laparoscopic adrenalectomy for pheochromocytomas in patients with tumors smaller or greater than 4 cm to assess safety of the procedure. METHODS A retrospective review was performed of laparoscopic adrenalectomies for pheochromocytoma by a single ...

Pheochromocytoma of the urinary bladder is often misdiagnosed as it is a rare tumor. In this report, we described a case with primary pheochromocytoma of the urinary bladder. We specifically conversed the diagnostic role of X-ray computed tomography and sonography to identify the location of tumor within urinary bladder compared to other malignant or benign tumors in the bladder, and exclude ot...

Pheochromocytoma is a rare tumour which is usually suggested by sustained or paroxysmal hypertension however the spectrum of the presentation of pheochromocytoma continues to expand and hypertension may be absent despite excess catecholamine secretion. The normotensive pheochromocytoma is a distinct entity and as in the case we report the presentation was quite unique as well as the intraoperat...

von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited syndrome characterized by a predisposition to various neoplastic lesions. To clarify the epidemiology and clinical characteristics of VHL-associated pheochromocytoma (PHEO) in Japan, we have summarized VHL-PHEO characteristics from a nationwide cross-sectional survey for VHL disease on the basis of the epidemiological study pr...

We report two cases of pheochromocytoma combined with tetralogy of Fallot who showed different clinical courses. Case 1 was a 45-year-old woman with a history of radical operation for tetralogy of Fallot at 20 years of age. She presented with sudden hypertensive attack, and was diagnosed with pheochromocytoma of the left adrenal gland. She was treated surgically, and her high plasma noradrenali...

Pheochromocytoma and Ganglioneuroblastoma are separate diseases and a rare combination in which the diagnosis can only be confirmed by pathological examination after tumor excision. We reported here a case of ganglioneuroblastoma encapsulated in pheochromocytoma. The patient is a woman, 73 years old, hypertensive, with hypothyroidism, associated for 15 years with hypercholesterolemia and hypert...

The dramatic presentation of pheochromocytoma in crisis is uncommon and is classically associated with a state of hemodynamic and sympathetic hyperactivity. The case of a 35-year-old man with an occult pheochromocytoma presenting with hypotension and cardiogenic shock shortly after beginning imipramine therapy is presented. Retrospectively, there was a history of emergency department, inpatient...

Aim: To study the presentation, surgical treatment and outcome of patients with adrenal masses. Methods: This is retrospective study of 15 patients who underwent adrenalectomy at Shaikh Zayed Hospital Postgraduate Medical Institute, Department of Urology over a period of six years between January 2006 to December 2011. In all cases adrenalectomy performed through open transabdominal approach. R...

Pheochromocytoma is a neuroendocrine tumor, characterized by an excess of catecholamine production, which results in paroxysmal or sustained hypertension, even hypertensive crisis. The classic triad of pheochromocytoma is paroxysmal headache, sweating and palpitation. Myocarditis is a rare manifestation of pheochromocytoma. We report 2 middle-aged women with a long history of hypertension and h...