PlXDOSO: TO assess the possible role Of experimental uveitogenic antigens (S-Ag, IRPB and recoverin) in human uveitis. Methods : Patients suffering from non-infectious bilateral UVeitiS and from the Ocular type of Behcet's disease were included in this study. Patients’ lymphocytes were tested for their possible in vitro anamnestic immune ~~SpClllS~ (specific blast transformation) to S-Ag, IRBP ...

Bilateral chronic anterior uveitis is an extra-articular feature of juvenile idiopathic arthritis. Although figures vary, uveitis occurs in approximately 11%-13% of patients with this disease and is most commonly associated with the female gender, oligoarthritis, and presence of antinuclear antibodies. The disease has an insidious onset and is often asymptomatic. Managing patients with juvenile...

Afatinib is a second-generation epidermal growth factor receptor (EGFR) inhibitor that has been shown to be effective against EGFR-mutated non-small cell lung cancer (NSCLC) resistant to conventional EGFR inhibitors such as gefitinib and erlotinib. Although ocular side effects of gefitinib and erlotinib have been reported, those for afatinib have yet to be definitively established. This report ...

Behçet's disease (BD) involves multisystem vasculitis of unknown origin. Ocular manifestations of BD mostly include bilateral panuveitis and retinal vasculitis, which are very challenging to treat. Interferon alfa-2a (IFN) has been recently introduced for treating refractory Behçet uveitis, mainly in Germany and Turkey. Nonetheless, there is so far no consensus about the ideal treatment regimen...

BACKGROUND Acute anterior uveitis has diverse causes and systemic associations. Inflammation is predominantly localised to the iris and pars plicata. Little is known about the in vivo effects of uveitis on ciliary body anatomy. METHODS Bilateral, high frequency, high resolution, ultrasound biomicroscopy was performed on consecutive patients with unilateral anterior uveitis to evaluate ciliary...

Introduction: Syphilis is a sexually transmitted, chronic, systemic infection caused by the spirochete Treponema pallidum. If left untreated, the disease progresses though 4 stages, with the potential to cause significant morbidity to any major organ of the body. Common syphilitic ocular manifestations, including anterior, intermediate and posterior uveitis, chorioretinitis, retinitis, retinal ...

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disorder defined by the combination of biochemical abnormalities, tubulointerstitial nephritis, and uveitis. We describe a 12-year-old female, presented with a ten-day history of fever, characterized by sudden onset and rapid spontaneous resolution in few hours, accompanied by shivering, extreme fatigue, and loss of appetite. La...