Tick-pathogen-host interactions have been closely studied to understand the molecular mechanisms of pathogen transmission for tick-borne diseases, including Lyme disease, babesiosis, spotted fever diseases, and Tick-borne encephalitis, among others. Such studies have yielded insights into disease processes and have identified promising candidates for vaccines against tick-borne diseases (Dai et...

Genome compression has been the subject of multiple studies in the past several years. In general, studies in this field can be grouped into two main categories: reference-based compression and non-reference based compression. Methods which do not use reference genomes exploit the repetitive nature of genomic sequences, and compress the input data by using variations over general-purpose compre...

The internet connectivity of client software (e.g., apps running on phones and PCs), web sites, and online services provide an unprecedented opportunity to evaluate ideas quickly using controlled experiments, also called A/B tests, split tests, randomized experiments, control/treatment tests, and online field experiments. Unlike most data mining techniques for finding correlational patterns, co...

Scyphomedusae undergo a predictable ontogenetic transition from a conserved, universal larval form to a diverse array of adult morphologies. This transition entails a change in bell morphology from a highly discontinuous ephyral form, with deep clefts separating eight discrete lappets, to a continuous solid umbrella-like adult form. We used a combination of kinematic, modeling, and flow visuali...

470 Extracardiac endothelium patterns embryonic coronary arterio-venous connections JM. Perez-Pomares1; E. Cano2; R. Carmona1; A. Ruiz-Villalba3; A. Rojas4; Y-Y. Chau5; KD. Wagner6; N. Wagner6; ND. Hastie5; R. Munoz-Chapuli1 University of Málaga, Málaga, Spain; Max Delbruck Center for Molecular Medicine, Berlin, Germany; University of Navarra, Pamplona, Spain; Centro Andaluz de Biologı́a Molecul...

Et Tu, Torsten? This critique of my Economic Policy paper generates many emotions. It is certainly an honor for my research to be taken seriously by such an eminent scholar as my friend Torsten Persson. And while any publicity is good, a negative citation dominates a positive one. There is irony; I came up with the original idea in a hallway conversation with Harry Flam a few feet from Persson’...

A traditional view of the nature of species holds that populations within species maintain genetic cohesion through substantial intraspecific gene flow and that the whole genome of a species is protected from interspecific gene flow by strong reproductive isolation. Both aspects of this view have been challenged. Reproductive barriers between recently evolved species can be incomplete and perme...

This paper describes and discusses the impacts of the passage of cold fronts on the vertical structure of the Carlos Botelho (Lobo-Broa) Reservoir as demonstrated by changes in physical, chemical, and biological variables. The data were obtained with a continuous system measuring 9 variables in vertical profiles in the deepest point of the reservoir (12 m) coupled with climatological informatio...

Two new species of Dolichothele Mello-Leitão, 1923 are described from Brazil and Bolivia, D. mottaisp. n. from Distrito Federal and the state of Goiás, Brazil, and D. camargorumsp. n. from the state of Rondônia, Brazil, and the La Paz region, Bolivia. Males of the two new species resemble Dolichothele bolivianum (Vol, 2001) in having a small subapical keel on the distal embolus and females in p...