Biocompatible polymers utilized for flexible encapsulations of implantable microsystems provide many advantages compared to widely used rigid titanium or ceramic packages. However, polymers alter their properties due to interactions with their environment, but especially for longterm implants, a reliable protective function of these materials is required. To investigate the protective function ...

The last decade has seen artificial blood vessels composed of natural polymer nanofibers grafted into human bodies to facilitate the recovery of damaged blood vessels. However, electrospun nanofibers (ENs) of biocompatible materials such as chitosan (CTS) suffer from poor mechanical properties. This study describes the design and fabrication of artificial blood vessels composed of a blend of CT...

Synthetic polymers belonging to the aliphatic polyester group have become highly promising biomaterials for reconstructive medicine. The purpose of the present work is a biological evaluation of lactide-glycolide co-polymer (PLGA) and its composites with carbon fibers (PLGA+CF) or hydroxyapatite (PLGA+HA). The cytotoxicity of the evaluated materials towards hFOB 1.19 human osteoblast-like cells...

By interrogating nature at the length scale of important biological molecules (proteins, DNA), nanotechnology offers great promise to biomedicine. We review here our recent work on nanofilm biomaterials: "nanoscopically" thin, functional, polymer-based films serving as biocompatible interfaces. In one thrust, films containing carbon nanotubes are shown to be highly antimicrobial and, thus, to b...

Introduction: During the last decades polymer therapeutics became more and more an emerging field of interest. An example which has already been intensively studied in clinical trials is the biocompatible polymeric backbone N-(2-hydroxypropyl)-methacrylamide (HPMA). Nevertheless, detailed knowledge about the biodistribution of polymeric drug-delivery systems in living organisms is still lacking...

In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications. PLGA is biocompatible and biodegradable, exhibits a wide range of erosion times, has tunable mechanical properties and most importantly, is a FDA approved polymer. In particular, PLGA has been extensively...

Using the thermal decomposition of organometallics method we have synthesized high-quality, iron oxide nanoparticles of tailorable size up to ~15nm and transferred them to a water phase by coating with a biocompatible polymer. The magnetic behavior of these particles was measured and fit to a log-normal distribution using the Chantrell method and their polydispersity was confirmed to be very na...

At present, 3D printing is experiencing a great boom. The demand for new materials also related to its expansion. This paper deals with manufacturing innovative polymer composite filaments suitable the Fused Filament Fabrication method in printing. As filler, common and uncostly glass beads were used mixed biocompatible biodegradable poly (ε-caprolactone), as matrix. material was characterized ...

The design and method for the production of an all-polymer microfluidic particle sorter, for use in biomedical applications, is described. The sorter is made from biocompatible materials with properties, such as high optical transparency, that make it useful in a biological laboratory. The method of sorting is designed to be gentle on biological species, using a method of guiding the particles ...

Microreactors fabricated with optically transparent inorganic polymers from two types of ceramic precursors using a UV-micro-imprinting process demonstrated reliable solvent resistance, biocompatible and capability for performing photo catalytic and organic synthetic reactions, which were compared with batch systems and glass based microreactors. It is for the first time that the polymer-based ...