نتایج جستجو برای: biological markers

تعداد نتایج: 619921  

2015
Marie Karlikova Ondrej Topolcan Olive T. J. Wolfe Vivian Barak Tomas Zima

1Central Laboratory of Immunoanalysis, Faculty Hospital in Pilsen and Faculty of Medicine in Plzen, Charles University in Prague, 300 00 Pilsen, Czech Republic 2Biomedical Center, Faculty of Medicine in Pilsen, Charles University in Prague, 323 00 Pilsen, Czech Republic 3Clinical Consultants, Inc., Glen Rock, NJ 07452, USA 4Hadassah Medical Center, Hebrew University, 911 20 Jerusalem, Israel 5F...

2004
Stuart G. Baker Barnett S. Kramer Philip C. Prorok

We provide a general framework for describing various roles for biomarkers in cancer prevention research (early detection, surrogate endpoint, and cohort identification for primary prevention) and the phases in their evaluation.

2017
Ying Huang Kailash Gulshan Truc Nguyen Yuping Wu

2016
Thomas M. Shiovitz Earle E. Bain David J. McCann Phil Skolnick Thomas Laughren Adam Hanina Daniel Burch

Accounting for subject nonadherence and eliminating inappropriate subjects in clinical trials are critical elements of a successful study. Nonadherence can increase variance, lower study power, and reduce the magnitude of treatment effects. Inappropriate subjects (including those who do not have the illness under study, fail to report exclusionary conditions, falsely report medication adherence...

2012
E Sã J Martín P Puig A Palanques

Introduction Conclusions References

2018
Michèle Natale Michael Behnes Seung-Hyun Kim Julia Hofmann Nadine Reckord Ursula Hofmann Johannes Budjan Siegfried Lang Martin Borggrefe Theano Papavassiliu Thomas Bertsch Ibrahim Akin

Following publication of the original article [1], the authors reported that there was a mistake in the Methods section → Measurements of biomarkers (page 6, line 3): 2000g should read 2500g. So, the correct sentence should be "All samples were obtained by venipuncture into serum monovettes® and centrifuged at 2500g for 10 min at 20 °C."

2011
Eiran Z. Gorodeski Udaya B. Kogalur Eugene H. Blackstone Mara Z. Vitolins JoAnn E. Manson Lisa W. Martin Ronald J. Prineas Michael S. Lauer

Journal: :Toxicology 2008
Federico M Goodsaid Felix W Frueh William Mattes

Biomarkers may be qualified using different qualification processes. A passive approach for qualification has been to accept the end of discussions in the scientific literature as an indication that a biomarker has been accepted. An active approach to qualification requires development of a comprehensive process by which a consensus may be reached about the qualification of a biomarker. Active ...

Journal: :Environmental Health Perspectives 1997
J C Barrett H Vainio D Peakall B D Goldstein

The 12th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC) considered the topic of methodologies for determining human and ecosystem susceptibility to environmental hazards. The report prepared at the meeting describes measurement of susceptibility through the use of biological markers of exposure, biological markers of effect, and biomarkers dire...

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