An emerging notion in systems biology is that biological networks have evolved to function well while their components behave stochastically. Thus, the dynamics in a biological network consist of two parts, deterministic and stochastic. A fundamental question is to find a quantitative relation between the two parts. We term such a relation as a deterministic-stochastic principle (DSP) and propo...

Background: RNA plays key role in many aspects of biological processes and its tertiary structure is critical for its biological function. RNA secondary structure represents various significant portions of RNA tertiary structure. Since the biological function of RNA is concluded indirectly from its primary structure, it would be important to analyze the relations between the RNA sequences and t...

Today, sustainable development is one of the important issues in regard to the economy of a country. This issue magnifies the necessity for increased scrutiny towards issues such as environmental considerations and product recovery in closed-loop supply chains (CLSCs). The most important motivational factors influencing research on these topics can be considered in two general groups: environme...

a novel algorithm for the fast detection of hubs in chemical networks is presented. thealgorithm identifies a set of nodes in the network as most significant, aimed to be the mosteffective points of distribution for fast, widespread coverage throughout the system. we showthat our hubs have in general greater closeness centrality and betweenness centrality thanvertices with maximal degree, while...

Network science is today established as a backbone for description of structure and function of various physical, chemical, biological, technological, and social systems. Here we review recent advances in the study of complex biological systems that were inspired and enabled by methods of network science. First, we present research highlights ranging from determination of the molecular interact...