The results in the management of pregnant women in idiopathic oligohydramnios using monitoring of major parameters of the biophysical profile of the functional maternal biosystem – amniotic structures – the fetus are given in this article. It was established that prenatal prognosis could be objectively performed on the basis of the main estimations of heart rate variability, amniotic fluid inde...

Voltage-gated sodium channels (VGSCs) play an important role in neuronal excitability. Regulation of VGSC activity is a complex phenomenon that occurs at multiple levels in the cell, including transcriptional regulation, post-translational modification and membrane insertion and retrieval. Multiple VGSC subtypes exist that vary in their biophysical and pharmacological properties and tissue dist...

Escherichia coli NikR, a repressor with homologs in other bacteria and archaea, was identified as a potential new member of the ribbon-helix-helix (beta-alpha-alpha) family of transcription factors in profile based sequence searches and in structure prediction experiments. Biophysical and biochemical characterization of the N-terminal domain of NikR show that it has many features expected of a ...

The density profile of an elastic fiber like DNA will change in space and time as ligands associate with it. This observation affords a new direction in single molecule studies provided that density profiles can be measured in space and time. In fact, this is precisely the objective of seismology, where the mathematics of inverse problems have been employed with success. We argue that inverse p...

Fisheries support livelihood of over half a billion of people globally. Many of these people live in coastal regions of developing countries; and have limited capacity to adapt and build resilience in the face of climate change.  This research assesses the biophysical and socioeconomic characteristics of fishers in four coastal communities, Komenda, Elmina, Cape coast and Morree, in Ghana. Stru...

Tree planting is widely promoted as a cost-effective natural climate solution, yet there are few evaluations of the implementation tree planting. Our analysis unique dataset on in Indian Himalayan state Himachal Pradesh shows that over half state’s budget for wasted plantations unlikely to survive and/or poorly designed achieve goal increasing forest cover. (and India more generally) has been i...