The objective of this article is to summarize the available technologies for biosensing applications in COVID-19. divided into three parts, an introduction technologies, mainstream and a review biosensors presents history inventing technology, which refers ISFET. resonant biosensor with example MEMS. principle optical biosensor, thermal biosensor. In second part, main use techniques, it was dis...

Highly crystalline ZnO nanoparticles with a pure phase and raspberry-like structure were synthesized using three different techniques (glycol-solvothermal, low-temperature solvothermal, coprecipitation methods). Physisorption analysis field emission scanning electron microscopy confirmed the large specific surface area of mesoporous–macroporous due to interstices aggregated agglomerated seconda...

In this work, a biosensing method based on in situ, fast, and sensitive measurements of ellipsometric parameters (Ψ, ∆) is proposed. Bare silicon wafer substrate is functionalized and used to bind biomolecules in the solution. Coupled with a 45° dual-drive symmetric photoelastic modulator-based ellipsometry, the parameters Ψ and ∆ of biolayer arising due to biomolecular interactions are determi...

Peptide nucleic acids (PNA) are a unique class of synthetic molecules that have a peptide backbone and can hybridize with nucleic acids. Here, a versatile method has been developed for the automated, in situ synthesis of PNA from a porous silicon (PSi) substrate for applications in gene therapy and biosensing. Nondestructive optical measurements were performed to monitor single base additions o...

A generic biosensing platform, based on nanostructured porous Si (PSi), Fabry-Pérot thin films, for label-free monitoring of heavy metal ions in aqueous solutions by enzymatic activity inhibition, is described. First, we show a general detection assay by immobilizing horseradish peroxidase (HRP) within the oxidized PSi nanostructure and monitor its catalytic activity in real time by reflective ...

We report a novel microwave plasma enhanced chemical vapor deposition strategy for the efficient synthesis of multilayer graphene nanoflake films (MGNFs) on Si substrates. The constituent graphene nanoflakes have a highly graphitized knife-edge structure with a 2–3 nm thick sharp edge and show a preferred vertical orientation with respect to the Si substrate as established by near-edge X-ray ab...

Label-free, nanoparticle-based plasmonic optical biosensing, combined with device miniaturization and microarray integration, has emerged as a promising approach for rapid, multiplexed biomolecular analysis. However, limited sensitivity prevents the wide use of such integrated label-free nanoplasmonic biosensors in clinical and life science applications where low-abundance biomolecule detection...