their lifetimes. Mild to moderate consumption (up to one drink/day for women and two drinks/day for men) has been shown to have beneficial cardiovascular effects, including a decreased risk of myocardial infarction and stroke, as well as overall decreased mortality (Box 154.1). Despite these possibly beneficial effects of alcohol, it has been found to be a top 10 cause of preventable deaths amo...

interleukin-1β (il-1β) is one of the most important cytokines which seems to have an important role in the inflammatory process in gingival and peri-implant tissues. the aim of this split-mouth study was to investigate the relationship between the concentration of il-1β in gingival crevicular fluid (gcf) and peri-implant crevicular fluid (picf) and clinical parameters such as plaque index (pi),...

Baicalein (BL), a potential cancer chemopreventative flavone, has been reported to inhibit cancer cell growth by inducing apoptosis and causing cell cycle arrest in various human cancer cell models. Delivery of BL via nanoliposomes has been shown to improve its oral bioavailability and long‑circulating property in vivo. However, the role of BL in the inhibition of human chronic myeloid leukemia...

The circadian rhythm is a physiological phenomenon that occurs in various organisms with cycle of about 24 hours. Light one the important environmental factors affecting biological rhythm. To clarify whether shift light spectrum can influence expression fish brain, total 175 European seabasses [body weight: 32.5 ± 0.71) g; body length: (13.78 0.35) cm] were exposed to white (WL), red (RL), yell...

The notions of int-soft filters, int-soft G-filters, regular int-soft filters, and MV-int-soft filters in residuated lattices are introduced, and their relations, properties, and characterizations are investigated. Conditions for an int-soft filter to be an int-soft G-filter, a regular int-soft filter, or an MV-int-soft filter are provided. The extension property for an int-soft G-filter is dis...

purpose to verify whether active recovery (ar) applied after a kickboxing match resulted in better performance in anaerobic tests when compared to passive recovery (pr). methods eighteen kickboxers volunteered to participate on a kickboxing match preceded and followed by anaerobic tests: squat jump (sj), the counter movement jump (cmj) and the upper-body wingate test. blood lactate (bl), heart ...

Background: Hip fracture is one of the most common problems in elderly that needs surgical repair. As, the majority ofthese patients have chronic diseases, they are at increased risk of peri-operative mortality and morbidity. The purposeof this study was to evaluate spinal anesthesia with bupivacaine vs bupivacaine in combination with lidocaine in termsof hemodynamic changes in patients undergo...

BACKGROUND Alcohol intake during pregnancy is considered to be a risk factor for child development. Child biomarkers of intrauterine alcohol exposure have been rarely studied. We investigated whether a meconium alcohol metabolite (ethyl glucuronide, EtG) was associated with cognitive development, ADHD-related behaviour and neurophysiological markers of attention and executive control of childre...

Obesity induces chronic inflammation and is an established risk and progression factor for triple-negative breast cancers, including basal-like (BL) and claudin-low (CL) subtypes. We tested the effects of dietary supplementation with ethyl esters of the marine-derived anti-inflammatory omega-3 fatty acids eicosapentaenoic and docosahexaenoic acid (EPA+DHA; Lovaza) on growth of murine BL and CL ...

In response to 5-hydroxytryptamine (5-HT), the type 1 serotonin receptors (5-HT1Rs) preferentially couple to the inhibitory G protein and elicit many physiological and behavioral processes. However, their regulation by intracellular protein kinases has not been fully investigated. In this study, we identified that glycogen synthase kinase-3 (GSK3) differentially regulates 5-HT1Rs. In receptor-e...