In this paper, we employ the known recursive construction methods to obtain some new existence results for large sets of t-designs of prime sizes. We also present a new recursive construction which leads to more comprehensive theorems on large sets of sizes two and three. As an application, we show that for infinitely many values of block size, the trivial necessary conditions for the existence...

In statistical planning of experiments, super-simple designs are the ones providing samples with maximum intersection as small as possible. Super-simple designs are also useful in other constructions, such as superimposed codes and perfect hash families etc. The existence of super-simple (v, 4, λ)-BIBDs have been determined for λ = 2, 3, 4 and 6. When λ = 5, the necessary conditions of such a d...

The objective of this thesis is to optimise the fragmentation at Boliden Minerals open pit mine Aitik. Blasting is one of the main operations in mining, and its performance has a major impact on the overall economy of the mine. The fragmentation process affects not only the local productivity and unit costs of the mining department. It also affects the performance of the subsequent comminution ...

Curupira is a 96-bit block cipher, with keys of 96, 144 or 192 bits, and variable number of rounds, an algorithm described at SBRC 2007. This paper1 presents impossible-differential, boomerang and higher-order multiset attacks on reduced-round versions of Curupira, that were not previously considered in the security analysis by its designers. Also, we provide security analyses based solely on t...

A 43-year-old man with pancytopenia and circulating blast cells was found to have acute megakaryoblastic leukemia. Bone marrow biopsy disclosed reticulin fibrosis with infiltration of blast cells. Cytogenic study showed 48,XY,+15,+18. The megakaryocytic origin of blast cells was confirmed by platelet peroxidase reaction at ultrastructural level. The spleen which had not been felt on admission i...

A 17-year-old previously healthy male presented with an incidental finding of pancytopenia and circulating blast cells in the peripheral blood. Bone marrow aspirate and biopsy showed a large population of blast cells. Blast cells showed variability in size, variable amount of cytoplasm, and vacuoles in the cytoplasm. Some contained azurophilic granules. The nuclei were irregular with folding an...

We run lots of BLAST searches. Typically, we’re searching DNA or protein sequences from a singlegenome or metagenomic dataset against a big database. Because of increased throughput from nextgeneration sequencing technologies, you’ll often end up with millions of sequences, so it’s no longer possible to BLAST all your sequences against a decent size database on a single machine or even a small ...