OBJECTIVES The objective of this study was to compare the predictive performance of bleeding risk-estimation tools in a cohort of patients with atrial fibrillation (AF) undergoing anticoagulation. BACKGROUND Three bleeding risk-prediction schemes have been derived for and validated in patients with AF: HEMORR(2)HAGES (Hepatic or Renal Disease, Ethanol Abuse, Malignancy, Older Age, Reduced Pla...

OBJECTIVE The aim of this study was to investigate the periodontal and oral hygiene status of 18-year-old Lithuanian adolescents. MATERIALS AND METHODS Cross-sectional data were collected by a multistage sampling approach that was used to draw a representative sample of 1063 adolescents attending schools. In total, 20 schools from the alphabetical list of educational institutions in Lithuania...

INTRODUCTION Asoprisnil, a novel orally active selective progesterone receptor modulator, is being studied for the management of symptomatic uterine leiomyomata. The exact mechanism of action is not yet discerned. The primary objectives of this double-blind, randomized, placebo-controlled study included evaluation of the effect of asoprisnil on uterine artery blood flow. Furthermore, we assesse...

By means of the fixed point index theory of strict set contraction operators, we establish new existence theorems on multiple positive solutions to a boundary value problem for second-order impulsive integro-differential equations with integral boundary conditions in a Banach space. Moreover, an application is given to illustrate the main result.

Aim of study: To evaluate the effectiveness of using uterine artery color Doppler and location of intrauterine copper device by three dimensional transvaginal ultrasound in relation to abnormal vaginal bleeding and pain. Methods: Three dimensional transvaginal ultrasound examinations were carried out to 180 women 3-6 months after IUD insertion. Seventy six women were suffering from pain (groupI...

Background: Supragingival plaque control is fundamental to the prevention and management of periodontal diseases. However significant proportions of all individuals fail to practice a high standard of plaque removal. The adjunctive use of chemicals would, therefore appear a way of overcoming deficiencies in mechanical tooth cleaning habits. This prospective, randomized positively controlled cli...

OBJECTIVE This study was designed to assess a newly developed toothbrush for efficacy in plaque removal, reduction of gingivitis and soft tissue bleeding, and retardation of stain formation over 30 days. METHODOLOGY Healthy adult subjects (N = 112) were admitted to the study, and randomly given a test toothbrush, (the elmex interX medium) or the control toothbrush, an ADA-Accepted flat-bristl...

more than 65 years old, and the use of antiplatelet agents is vastly more common than that. Patients with inherited bleeding disorders will likely present to the emergency department (ED) for treatment of abnormal bleeding at some point during their lifetime, and ED visits for bleeding in patients who are taking antithrombotic agents are not uncommon. The clinician must be familiar with these d...

BACKGROUND Dual-antiplatelet therapy with aspirin and a thienopyridine is a cornerstone of treatment to prevent thrombotic complications of acute coronary syndromes and percutaneous coronary intervention. METHODS To compare prasugrel, a new thienopyridine, with clopidogrel, we randomly assigned 13,608 patients with moderate-to-high-risk acute coronary syndromes with scheduled percutaneous cor...