cytokine production  in response to allergens may influence the development of atopy- predisposing immune responses, initializing the  early programming of  allergy and  asthma. vitamin d  intake  may be  protective  due  to  its  immunoregulatory properties,  that  may contribute  to  influence the expression of  the atopic phenotype  initiated in early life. the objective of our study was to ...

Background: Regulatory T Cells (Tregs) and Myeloid-Derived Suppressor Cells (MDSCs) are two main regulatory cells modulating the immune responses in inflammation and cancer. Objective: To investigate and compare Tregs and MDSCs in peptic ulcer and gastric cancer. Methods: Patients with dyspepsia were selected and divided into three groups of non-ulcer dyspepsia (NUD, n=22), peptic ulcer disease...

Background  In recent years, many researchers haveattempted to cure diabetes by using stem cells technology. Stem cells from different sources have capabilityto differentiateinto insulin producing cells (IPCs) by different methods. The obstaclesof these methods aretheirexpensive materials and complexity ofmethodswhichare practicallydisadvantagesfor producing enough transplantableIPCs that can ...

Background: Taking the drivers' health into account from different perspectives is important. This study aimed to examine how heavy vehicle drivers' blood parameters are related to their road accident risk. Materials & Methods: A descriptive study was conducted among 200 drivers of heavy vehicles. The blood parameters were determined based on the medical records of drivers, as well as data on ...

background: systemic lupus erythematosus (sle) is a multisystem autoimmune disease. emerging data suggests that t helper 17 (th17) cells play a pathogenic role in sle and the increased number of these cells correlates with disease activity. in recent years, 1α, 25-dihydroxyvitamin d3 (1,25vitd3) has been considered as an immunomodulatory factor. objective: to investigate the effect of 1,25vitd3...