Traumatic injury can cause chronic inflammation that lasts several months to years. Interleukin-10 plays an important role in the repair of tissue fibrosis and accelerates wound healing. The active compounds secondary metabolites Moringa leaves include flavonoids, saponins, alkaloids, tannins accelerate closure act as anti-inflammatory effect help vasoconstriction blood vessels so minimize sign...

In this study, a rapid multi-mycotoxin approach was developed for biomonitoring and quantification of 27 important mycotoxins and mycotoxin metabolites in human blood samples. HPLC-MS/MS detection was used for the analysis of dried serum spots (DSS) and dried blood spots (DBS). Detection of aflatoxins (AFB1, AFB2, AFG1, AFG2, AFM1), trichothecenes (deoxynivalenol, DON; DON-3-glucoronic acid, DO...

Organophosphorous pesticides (OPs) are suspected of altering reproductive function by reducing brain acetylcholinesterase activity and monoamine levels, thus impairing hypothalamic and/or pituitary endocrine functions and gonadal processes. Our objective was to evaluate in a longitudinal study the association between OP exposure and serum levels of pituitary and sex hormones. Urinary OP metabol...

Background: The application of phytogenic additives in the form of essential oils have attracted considerable attention in poultry industry. OBJECTIVES: An experiment was conducted to evaluate effects of the blends of essential oils (EO) isolated from some medicinal plants including savory, thyme, fennel and rosemary on performance, blood metabolites, intestinal microflora, and meat quality of...

Abstract Background Endoscopy has been the gold standard for assessing activity in Pediatric Crohn disease (pCD); however, it is limited by its invasiveness and partial assessment of small intestine transmural inflammation. To that end, Inflammatory Crohn's MRE Index (PICMI) a valid, reliable, non-invasive, responsive index includes inflammation when activity. The pathogenesis pCD remains poorl...

Estimation of age dependent changes of the lipid peroxidation (LPO) intensity, content of stable metabolites of nitrogen oxides (NO) and antioxidant enzyme activities in rat blood serum in conditions of experimental postinfarction cardiosclerosis (PICS) is carried out. Initiation of the postinfarction remodeling of animals has been carried out with coronary occlusion, definition of LPO and NO m...

Introduction The accumulation of benzodiazepines (BZD) or their metabolites in critically ill patients may prolong wakening times after its discontinuation increasing their morbidity and leading to the overuse of complementary testing to assess neurological function. Route urine/serum determination of BZD are used in some centers to determine BZD clearance, however the correlation of BZD urine/...