Sciatic neuropathy is the second most common neuropathy of the lower extremity and a common cause of foot drop. This article reviews the anatomy, clinical features, pathophysiology, and electrodiagnostic assessment of sciatic neuropathies. There are multiple potential sites of pathology, determined in part by the mechanism of insult, including trauma, compression, masses, inflammation, and vasc...

A patient is described who developed right side hemineglect after a right cerebellar lesion. This spatial disorder was interpreted as a secondary effect of a deficit of the motor organisation in the right hemispace due to left frontal diaschisis. The pathological base may be the interruption of a highly integrated system which includes the lateral cerebellum and the contralateral frontal lobe.

We performed epi-mode pump-probe imaging of melanin in excised human pigmented lesions and both hemoglobin and melanin in live xenograft mouse melanoma models to depths greater than 100 µm. Eumelanin and pheomelanin images, which have been previously demonstrated to differentiate melanoma from benign lesions, were acquired at the dermal-epidermal junction with cellular resolution and modest opt...

The excitability of the motor cortex to magnetic stimulation was evaluated in seven patients with cerebellar lesions (six patients with a unilateral lesion) and in 20 control subjects. Magnetic motor threshold was defined at rest. In all but one of the patients with a hemicerebellar lesion the threshold was higher in the motor cortex contralateral to the impaired hemicerebellum and the right/le...

Compared to cortical lesions, spatial neglect following subcortical stroke is most frequently seen as a mild and transient phenomenon. Since this assumption is based on only few observations, we reexamined the prognosis and severity of spatial neglect in patients with circumscribed right-sided basal ganglia or thalamic lesions in the acute and in the chronic phase of the stroke. On average, 1.1...

. Where the Story Begins The incidence of cervical cancer in the US has declined dramatically over the last half century and continues to decline to this day. In 1975, the incidence of cervical cancer was 14.8 per 100,000 women; by the year 2013 that number was only 6.4 per 100,000. Similarly, the mortality due to cervical cancer during the same period was reduced from 5.6 to 2.3 women per 100,...

HAART: highly active antiretroviral therapy INTRODUCTION Oral melanoma accounts for approximately 1% of all melanomas. In contrast to cutaneous melanoma, the risk factors for development of oral melanoma are largely unknown. Immunosuppressive states, including HIV infection and iatrogenic immunosuppression, are associated with an increased risk of melanoma development. Pregnancy has not been fo...

most common sexually transmitted infections (STIs), is the primary cause of cervical cancer. HPV infection is a necessary but not sufficient precursor to cervical cancer. While the cumulative lifetime incidence of acquiring HPV is 70 to 80 percent in many countries, the vast majority of women with HPV infection will not develop cancer (see PATH’s fact sheet, Natural History of Cervical Cancer)....

This study develops a spectroscopic algorithm for detection of cervical high grade squamous intraepithelial lesions (HSILs). We collected reflectance and fluorescence spectra with the quantitative spectroscopy probe to measure nine spectroscopic parameters from 43 patients undergoing standard colposcopy with directed biopsy. We found that there is improved accuracy for distinguishing HSIL from ...

BACKGROUND Acute symmetric deep cerebellar lesions suggest toxic exposure. OBJECTIVE To describe a patient with striking neurologic and magnetic resonance image features. DESIGN Case report. SETTING Emergency department and office. METHODS Personal observation. RESULTS A middle-aged man had a day of unsteadiness, followed by acute and pronounced cerebellar signs. The degree of disabil...