UNLABELLED BACKGROUND; Bone aspergillosis remains a rare but potentially devastating fungal disease. Although voriconazole is effective for invasive pulmonary aspergillosis, evidence of its efficacy for aspergillosis located in bone is limited. METHODS We report our experience with voriconazole in 4 cases of invasive bone aspergillosis. In addition, all cases of probable and definite bone asp...

Matrix metalloproteinases (MMPs) play important roles in the invasion and metastasis to soft tissues of carcinomas including, oral squamous cell carcinomas (SCCs). Although, osteoclastic bone resorption is an important step in bone involvement in a variety of malignancies, the mechanism of bone involvement of oral SCC remains unclear. Once cancer cells arrest in bone, the bone is a storehouse o...

Extranodal NK/T-cell lymphoma, nasal type, is an aggressive EBV-associated lymphoma that mainly involves the nasal cavity but has also been reported to involve other extranodal sites without nasal involvement. In contrast to aggressive NK cell leukemia (a marrow-based aggressive leukemia of NK-cell origin); extensive bone marrow and blood involvement is extremely uncommon by nasal type NK/T lym...

enchymal dysplasia of bone that is diagnosed by a characteristic linear cortical hyperostosis with a flowing candle wax appearance (1-3). It commonly affects long bones, usually in the lower limb and on one side of the body. The involvement of flat bones is rare (1, 2). In addition, bilateral involvement is extremely rare, with only one case of long tubular bones with a symmetric distribution r...

OBJECTIVE The present study was aimed at investigating bone involvement secondary to rotator cuff calcific tendonitis at ultrasonography. MATERIALS AND METHODS Retrospective study of a case series. The authors reviewed shoulder ultrasonography reports of 141 patients diagnosed with rotator cuff calcific tendonitis, collected from the computer-based data records of their institution over a fou...

amyloidosis includes a wide range of disorders characterized by deposition of amyloid in different organs and tissues. localized gingival enlargement due to accumulation of amyloid without involvement of other organs is a very rare condition. this article describes a 31-year-old male patient with amyloidosis involving only the periodontium of the anterior mandibular teeth with localized severe ...

BACKGROUND Bone sarcoidosis is rare manifestation of disease usually accompanied with pulmonary involvement. Until today, exact prevalence of bone sarcoidosis is not known, since reported prevalence varies widely depending on the studied population and the used diagnostic techniques. OBJECTIVE To determine the prevalence of bone involvement and distribution pattern in active chronic sarcoidos...

We report a case of pure red cell aplasia (PRCA), which was initially suspected as a result of bone marrow involvement of diffuse large B cell lymphoma. Persistent anemia without an obvious cause was observed in a 47-yr-old man diagnosed with relapsed diffuse large B cell lymphoma. The bone marrow study showed only erythroid hypoplasia without the evidence of bone marrow involvement with lympho...

Myeloid sarcoma is a rare tumor mass with extra medullary growth pattern, composed of myeloblast or immature myeloid cells. (MS) distinct clinical presentation acute leukemia (AML) where less than 1% patients present prominent disease which most commonly involves the bone, skin, lymph node, soft tissues, gastrointestinal tract testes. The recommended treatment regimen in isolated bone marrow in...

osteoma is a benign bone-forming tumor that usually arises in the craniofacial bones and rarely in the long bones. clavicular involvement is extremely rare. we report a 51-year-old woman with osteoma of the left clavicle. radiograph of the left shoulder showed a well-defined lobulated blastic mass in the proximal and mid-portion of the left clavicle. bone scintigraphy was performed 4 hours afte...