نتایج جستجو برای: bone scaffold

تعداد نتایج: 326016  

Journal: :Advanced healthcare materials 2015
Neety Sahu Prakash Baligar Swati Midha Banani Kundu Maumita Bhattacharjee Snehasish Mukherjee Souhrid Mukherjee Florian Maushart Sanskrita Das Marko Loparic Subhas C Kundu Sourabh Ghosh Asok Mukhopadhyay

Recent years have witnessed the advancement of silk biomaterials in bone tissue engineering, although clinical application of the same is still in its infancy. In this study, the potential of pure nonmulberry Antheraea mylitta (Am) fibroin scaffold, without preloading with bone precursor cells, to repair calvarial bone defect in a rat model is explored and compared with its mulberry counterpart...

Journal: :Journal of biomedical materials research. Part A 2011
E Prosecká M Rampichová L Vojtová D Tvrdík S Melčáková J Juhasová M Plencner R Jakubová J Jančář A Nečas P Kochová J Klepáček Z Tonar E Amler

Collagen/hydroxyapatite (HA) composite scaffolds are known to be suitable scaffolds for seeding with mesenchymal stem cells (MSCs) differentiated into osteoblasts and for the in vitro production of artificial bones. However, the optimal collagen/HA ratio remains unclear. Our study confirmed that a higher collagen content increased scaffold stiffness but that a greater stiffness was not sufficie...

Journal: :Frontiers in Bioengineering and Biotechnology 2016

2014
Jared O Cooper Joel D Bumgardner Judith A Cole Richard A Smith Warren O Haggard

The tendon/ligament-to-bone interface has a complex organization to enable transfer of forces through the tendon/ligament to the bone. The purpose of this study is to create a co-culture environment enabling a tissue-specific tendon region and tissue-specific bone region on a degradable scaffold, using NIH 3T3 fibroblast-deposited extracellular matrix and MC 3T3 osteoblast-deposited extracellul...

Journal: :EAI Endorsed Trans. Future Intellig. Educat. Env. 2016
Symeon Symeonidis Carmen Torres-Sánchez Chinthana Panagamuwa William G. Whittow

In this paper the dielectric properties of an implanted bioresorbable scaffold that is being used for the acceleration of the healing process of a fractured bone have been investigated. An implanted antenna system is presented for the monitoring of the resorption rate of the scaffold, which gives an indication on the healing process of the bone fracture. A simulation model of a three layer body...

Journal: :Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010
Paul R T Kuzyk Emil H Schemitsch John E Davies

The aim of this study was to compare angiogenesis and osteogenesis occurring within 8.0 mm diaphyseal defects created in canine tibiae treated using autograft or a biodegradable bone scaffold. All tibiae were reamed to 7.0 mm and fixed with a 6.5-mm statically locked intramedullary nail. Each of the 18 canines as allotted to one of three treatment groups: (1) left empty (N = 5), (2) treated wit...

Journal: :International Journal of Molecular Sciences 2018

2015
Jin-Young Park Cheryl Yang Im-Hee Jung Hyun-Chang Lim Jung-Seok Lee Ui-Won Jung Young-Kwon Seo Jung-Keug Park Seong-Ho Choi

BACKGROUND The aim of this study was to characterize the efficacy of nano-hydroxyapatite-coated silk fibroin constructs as a scaffold for bone tissue engineering and to determine the osteogenic effect of human dental pulp and periodontal ligament derived cells at an early stage of healing in rabbits. 3D silk fibroin constructs were developed and coated using nano-hydroxyapatite crystals. Dental...

2015
Akihito Kato Hirofumi Miyaji Ryosuke Ishizuka Keisuke Tokunaga Kana Inoue Yuta Kosen Hiroyuki Yokoyama Tsutomu Sugaya Saori Tanaka Ryuji Sakagami Masamitsu Kawanami

UNLABELLED Objective : Biomodification of the root surface plays a major role in periodontal wound healing. Root surface modification with bone morphogenetic protein (BMP) stimulates bone and cementum-like tissue formation; however, severe ankylosis is simultaneously observed. Bio-safe collagen hydrogel scaffolds may therefore be useful for supplying periodontal ligament cells and preventing an...

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