BACKGROUND Blood oxygen saturation (BOS) is decreased in a low-compliant, overactive obstructed bladder. The objective of this study is to determine the effect of Sildenafil (SC) on bladder function and BOS) in an in vivo animal model of bladder outlet obstruction. METHODS Thirty-two guinea pigs; sham operated (n = 8), sham operated + SC (n = 8), urethrally obstructed (n = 8) and urethrally o...

INTRODUCTION A recent pilot study noted clinical benefit of macrolide therapy in the management of six lung transplant recipients with bronchiolitis obliterans syndrome (BOS), a condition previously regarded as irreversible. OBJECTIVE To examine the effect of low-dose macrolides on lung function in lung allograft recipients with established BOS and to assess whether this benefit is sustained....

CD59 is a complement regulatory protein that inhibits membrane attack complex formation. A soluble form of CD59 (sCD59) is present in various body fluids and is associated with cellular damage after acute myocardial infarction. Lung transplantation (LTx) is the final treatment for end-stage lung diseases, however overall survival is hampered by chronic lung allograft dysfunction development, wh...

PURPOSE The development of bronchiolitis obliterans syndrome (BOS) after allogeneic hematopoietic stem cell transplantation (HSCT) deteriorates patients' quality of life. This study aimed to analyze the prevalence, clinical features, risk factors and prognostic factors of BOS. MATERIALS AND METHODS This retrospective study included patients who underwent allogeneic HSCT from January 2002 to D...

Azithromycin reduces airway inflammation and improves forced expiratory volume in 1 s (FEV₁) in chronic rejection or bronchiolitis obliterans syndrome (BOS) after lung transplantation (LTx). Azithromycin prophylaxis might prevent BOS. A double-blind randomised controlled trial of azithromycin (n = 40) or placebo (n = 43), initiated at discharge and administered three times a week for 2 yrs, was...

0 0 Bet v 4 0 0 0 0 0 0.52 0 0 0 0 0 Bla g 1 0 0 0 0 0 0 0 0 0 0 0 Bla g 2 8.99 6.38 3.35 1.93 1.81 0 0 0 0 0 0 Bla g 5 20.09 0 0 0 0 0.23 0 0 0 0 0 Bla g 7 0 0 0 0 3.14 0 0 0 0 0 0 Blo t 5 0 0 0 0 0 0 0 0 0 0 0 Bos d 4 0 0 0 0 0 0 0 0 0 0 0 V Bos d 4 0 0 0 0 0 0 0 0 0 0 0 Bos d 5 3.71 0 0 0 0.92 0 0 0 0 0 0 V Bos d 5 37.66 21.94 9.83 3.71 5.35 0 0 0 0 0 0 Bos d Lactoferrin 32.92 14.67 7.56 4.1...

In this study, we genotyped 117 autosomal single nucleotide polymorphisms using a DigiTag2 assay to assess the genetic diversity, structure and relationships of 16 Eurasian cattle populations, including nine cattle breeds and seven native cattle. Phylogenetic and principal component analyses showed that Bos taurus and Bos indicus populations were clearly distinguished, whereas Japanese Shorthor...

We explored the destabilizing effect of visual field motion as the base of support (BOS) and the field of view (FOV) were narrowed. Visual field motion was achieved using an immersive virtual environment (scene) that moved realistically with head motion (natural motion) and translated sinusoidally at 0.1Hz in the fore-aft direction (augmented motion). Natural motion was presented in stereo whil...

Opitz C trigonocephaly (or Opitz C syndrome, OTCS) and Bohring-Opitz syndrome (BOS or C-like syndrome) are two rare genetic disorders with phenotypic overlap. The genetic causes of these diseases are not understood. However, two genes have been associated with OTCS or BOS with dominantly inherited de novo mutations. Whereas CD96 has been related to OTCS (one case) and to BOS (one case), ASXL1 h...

OBJECTIVES Increased concentrations of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzo-furans (PCDFs) in pooled blood samples from workers at municipal waste incinerators have been reported. This study was undertaken to confirm these results in individual blood samples from potentially exposed and unexposed workers at municipal waste incinerators compared with matched unex...