The aim of this study was to prepare orally disintegrating tablets (ODTs) containingdexamethasone (DEX) by direct compression method with sufficient hardness and rapiddisintegration time. In order to save time, money, and human resources in designing andimprovement of formulation, the statistical software Design Expert is used. Box–Behnkenresponse surface methodology was applied to evaluate and...

The objectives of this work were to optimize hydro-distillation extraction Salvia officinalis L. essential oil (SoEO) and evaluate the in vitro scavenging capacity free radicals DPPH·, NO·, ABTS+, ability reduce Fe3+. optimization SoEO by was carried out using response-surface methodology Box–Behnken. cytotoxicity anti-proliferative capacities evaluated measuring cell viability then modeled. Tw...

The present study aims to enhance the bioavailability of Blueberry by formulating it as nanosuspension. mainly consists ofanthocyanins which have strong antihyperlipidemic activity but suffers from low causes hindrances in itstherapeutic treat hyperlipidemia. Hence improve its bioavailability, nanosuspension blueberry was prepared. BoxBehnken design applied predict effect independent variables ...