background: otalgia and bell’s palsy are rare manifestations of metastasis and the most common presentation of an inflammatory process in the temporal bone. case presentation: this article explains a 34-year-old woman with breast cancer who presented with cranial nerve palsy symptoms. the 7th and 8th cranial nerves were involved in the metastatic phase and then hoarseness was added to her sympt...

Nuclear magnetic resonance (NMR) has been used to detect the chemicals earlier before the clinical application of magnetic resonance imaging (MRI). Since late 1980s, magnetic resonance spectroscopy (MRS) became popular with the advancement of MRI. Previous studies on in vitro NMR and in vivo MRS elucidate the effectiveness of its clinical application in different areas. We performed this study,...

A 28-year-old woman presented with a rare case of endodermal cyst located ventral to the lower brain stem manifesting as recurrent aseptic meningitis. Computed tomography and magnetic resonance imaging demonstrated a cystic mass located ventral to the lower brain stem and extending from the prepontine to the upper cervical (C-2) cistern. The lesion was totally removed through a retrosigmoid cra...

A 4-year-old male presented with rapid-onset cranial nerve palsy and ataxia. Brain magnetic resonance imaging (MRI) revealed a pontine mass lesion with discordant conventional and advanced imaging. A stereotactic core biopsy revealed glioblastoma with immunostaining suggestive of histone H3K27M and TP53 mutation, consistent with diffuse intrinsic pontine glioma. MRI 3 months after radiotherapy ...

The pineal region is an unusual site for brain metastasis and most metastatic pineal lesions are asymptomatic. A 53 year-old man presented with severe headache, limitation of upward gaze and diplopia. The patient's neurological examination was unremarkable. Magnetic resonance imaging (MRI) scans of the brain demonstrated a 1.5 x 2 cm well demarcated solitary mass in the pineal region with hydro...

Brain parenchymal involvement by mantle cell lymphoma is rare and confers a grim prognosis. More commonly, patients with central nervous system manifestations of mantle cell lymphoma have leptomeningeal involvement on radiographic studies with malignant cells found in the cerebrospinal fluid. Risk factors for central nervous system involvement include a high proliferation index, bone marrow inv...

Acute pure motor hemiparesis is a clinical syndrome of isolated hemiparesis usually related to lacunar infarction, although other etiologies have been described. We recently encountered three patients with the abrupt onset of pure motor hemiparesis as the initial manifestation of primary or metastatic brain tumor. In each patient, early computed tomography demonstrated a nonhemorrhagic, right f...

The objective of this study is to present a potential mechanism for traumatic brain injury resulting from a lateral blunt impact to the head during SUV-to-pedestrian impact. We developed an AM50 percentile model of the human head, and the mechanical response predicted by the model was validated against available cadaveric test data. It was found that the traction force due to the inertia of the...

Acute pure motor hemiparesis is a clinical syndrome of isolated hemiparesis usually related to lacunar infarction, although other etiologies have been described. We recently encountered three patients with the abrupt onset of pure motor hemiparesis as the initial manifestation of primary or metastatic brain tumor. In each patient, early computed tomography demonstrated a nonhemorrhagic, right f...

Although malignant melanoma (MM) most frequently tends to metastasize the regional lymph nodes, liver, lung and brain, several unusual sites of metastasis have been described in literature. Among these, metastatic involvement gallbladder or uterus represents an exceptional event, usually associated with diffuse disease observed as autopsy finding. In this paper, we present two cases isolated MM...