Background: Dental Pulp Stem Cells (DPSCs) are multipotent mesenchymal stem cells. DPSCs can renew themselves and differentiate into various cell types such as adipocytes, osteocytes, neurons, etc. DPSCs possess immunomodulatory properties and can inhibit peripheral blood mononuclear cell (PBMC) proliferation. Recent studies showed that conditioned-medium mesenchymal stem cells also had immunos...

Introduction: Abusing drugs such as morphine continues to be a serious medical and social problem. Defining a habit that increases the devastating effect such as compulsive use and craving is necessary. Methods: This experiment was designed in four groups 1) group-housed (GH) 2) isolation 3) group-housed morphine-treated (GHMT) (4) isolated-housed morphine-treated (IHMT). Rats were received mor...

Background: Chemotherapy or irradiation is associated with impaired fertility. The aim of this study was to investigate the possible protective role of testosterone enanthate (TE) on the proliferative activity, plasma testosterone level and morphometry of epithelial cells of seminal vesicles in busulfan-induced spermiotoxicity. Materials and Methods: Sprague- Dawley rats were divided into 4 gro...

BACKGROUND Genotoxic stress, such as by exposure to bromodeoxyuridine (BrdU) and cigarette smoke, induces premature cell senescence. Recent evidence indicates that cellular senescence of various types of cells is accelerated in COPD patients. However, whether the senescence of airway epithelial cells contributes to the development of airway diseases is unknown. The present study was designed to...

Abstract Despite advances in solid tumor biology and oncology, pediatric adult primary brain cancer metastasis to the harbor dismal prognosis poor outcomes. One avenue overcome these clinical challenges is through developing robust immunotherapy better target tumor. Our group has previously shown that adoptive cellular therapy (ACT) provides therapeutic benefit against central nervous system (C...

PURPOSE Stem cell (SC)-containing limbal basal epithelium and transient amplifying cell (TAC)-containing corneal basal epithelium lie on different mesenchymal matrices. The gap junction protein connexin 43 (Cx43) is absent in the limbal basal epithelium but is present in the corneal basal epithelium, suggesting that the expression of Cx43 denotes SC differentiation into TACs. Amniotic membrane ...

The selective incorporation of 5-bromodeoxyuridine (BrdU) into mitochondrial DNA (mit-DNA) in the LM(TK") ChD cell line, a thymidine kinase-deficient derivative of L, fibrobla8ts with persistent mitochondrial enzyme activity, has been utilized to specifically damage mit-DNA by 'visible' light irradiation. ('Visible light' indicates the source of light used, although the components most active p...

PURPOSE A common treatment for motility disorders of the extraocular muscles (EOMs) is a resection procedure in which there is surgical shortening of the muscle. This procedure results in rotation of the globe toward the resected muscle, increased resting tension across the agonist-antagonist pair, and stretching of the elastic components of the muscles. In the rabbit, due to orbital constraint...

The selective incorporation of 5-bromodeoxyuridine (BrdU) into mitochondrial DNA (mit-DNA) in the LM(TK-) ClID cell line, a thymidine kinase-deficient derivative of L fibroblasts with persistent mitochondrial enzyme activity, has been utilized to specifically damage mit-DNA by 'visible' light irradiation. ('Visible light' indicates the source of light used, although the components most active p...