نتایج جستجو برای: bupleurum

تعداد نتایج: 304  

2012
Seong-Mo Kim Sang-Chan Kim In-Kwon Chung Woo-Hyun Cheon Sae-Kwang Ku

Bupleuri Radix (BR), the dried roots of Bupleurum falcatum L., has been used in folk medicine as an antiinflammatory and antioxidative agent. The aqueous extract of BR was evaluated for its possible ameliorative effect in the regulation of hyperthyroidism in l-thyroxine- (LT4-) induced rat model. After oral administration of 300, 150, and 75 mg/kg of BR extracts, once a day for 15 days from 12t...

Journal: :Planta medica 2017
Xin Liu Simone Latkolik Atanas G Atanasov Olaf Kunert Eva-Maria Pferschy-Wenzig Elke H Heiss Clemens Malainer Andreas Schinkovitz Manfred Kollroser Verena M Dirsch Rudolf Bauer

The roots of Bupleurum chinense have a long history in traditional medicine to treat infectious diseases and inflammatory disorders. Two major compounds, saikosaponins A and D, were reported to exert potent anti-inflammatory activity by inhibiting NF-κB. In the present study, we isolated new saikosaponin analogues from the roots of B. chinese interfering with NF-κB activity in vitro. The methan...

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