Introduction: Loss of inhibitory output from Purkinje cells leads to hyperexcitability of the Deep Cerebellar Nuclei (DCN), which results in cerebellar ataxia. Also, inhibition of small-conductancecalcium-activated potassium (SK) channel increases firing rate  f DCN, which could cause cerebellar ataxia. Therefore, SK channel activators can be effective in reducing the symptoms of this disease, ...

in the current study, we assessed the role of transient receptor potential (trp) channels on avoidance memory and anxiety states in ca3 area of the hippocampus. we explored the anxiety and avoidance memory states using test-retest protocol in the elevated plus maze to understand whether trp channels can affect the above mentioned states in ca3 area. to investigate the consolidation phase of mem...

One of the problems of existing irrigation networks is seepage phenomena. Seepage problem and its control in irrigation channels is one of the most important issues in the design, construction, maintenance and operation of these channels. In this study, simulated the rate of seepage and phreatic lines in the Mianab irrigation and drainage channels located in the Karun basin using mathematical t...

OBJECTIVE Coronary artery bypass grafting is currently the best treatment for dialysis patients with multivessel coronary artery involvement. Vasoplegic syndrome of inflammatory etiology constitutes an important postoperative complication, with highly negative impact on prognosis. Considering that these patients have an intrinsic inflammatory response exacerbation, our goal was to evaluate the ...

BACKGROUND Extracranial-to-intracranial (EC-IC) arterial bypass is a technically demanding procedure used to treat complex cerebral artery diseases. The indications, proper surgical techniques, and outcomes of this procedure have been under debate over the recent decades. METHODS Between January 2004 and December 2012, 28 patients, including patients with cerebral artery occlusion, intracrani...

general concept and major emphasis on off-pump coronary artery bypass surgery (opcab) is maintaining quality of care and patient safety while reducing cost and resource utilization. opcab probably avoids the potential complications of cardiopulmonary bypass. however its acceptance depends on clinical and economic outcome. the aim of this study is to compare clinical and economic outcome of off-...

Graphene exhibits fascinating prospects for preparing high-performance membranes with fast water transport, due to its low friction and extreme thinness. However, graphene-assembled membranes, each molecule passing through the membrane should bypass many graphene sheets, which lengthens molecular pathways increases mass transfer resistance. Herein, a nanomesh (GNM) is fabricated that inspired b...

Trapping and storing light for arbitrary time lengths in open cavities is a major goal of nanophotonics, with potential applications ranging from energy harvesting to optical information processing. Unfortunately, however, the resonance lifetime conventional resonators remains finite, even limit vanishing material absorption, as result radiation loss. In this context, bound states continuum (Bi...

OBJECTIVE Selected patients appear to benefit from off-pump coronary artery bypass compared with conventional coronary artery bypass with cardiopulmonary bypass. It is unknown whether elderly patients undergoing isolated coronary artery bypass grafting operations derive any benefit when performed off-pump. We hypothesized that off-pump coronary bypass offers a greater operative benefit to elder...

this study aims to inspect the performance of the wastewater treatment system of the pars oil refinery. quantity and quality of wastewater are determined through samplings and measurements. the performance of system is evaluated considering total suspended solids, total dissolved solids, phosphate, chemical oxygen demand, biochemical oxygen demand, ammonia nitrogen, furfural, oil and ph. for pr...