BACKGROUND Complement (C) is a crucial part of the innate immune system and becomes over activated during malaria, resulting in depletion of C components, especially those for lectin pathway (LP), thereby compromising the host's innate defense. In this study, involvement of P. falciparum antigens in C activation was investigated. METHODS A highly synchronous culture of the Dd2 clone of P. fal...

in view of the increase in saccharomyces cerevisiae mannan content, the culture condition for s.cerevisiae were optimized in this study. the influence of culture condition such as original ph, inoculum size, and temperature on mannan production were evaluated using response surface methodology. the mathematical model was established by the quadratic rotary combination design. with the order of ...

The aim of this study was to optimize candidate antigen proteins for serological screening of Chlamydia trachomatis infection. C. trachomatis positive serum and swabs of genital secretions were collected from 50 patients in the Tianjin Medical University General Hospital, as well as from 30 patients negative for C. trachomatis. Samples were assessed by colloidal gold assay in a sexually transmi...

The effect of sodium and magnesium chloride in 1 and 2 m concentration at temperatures of 37 and 50 C on type C, strain 149, foot-and-mouth disease virus during storage for 6 days was studied. The exclusively passaged cattle strain and its tissue culture-adapted line were compared. Preparations of the various chemicals and their concentrations were made directly in suspensions of the virus, whi...