Both genetic and environmental factors are involved in the development of cancer; some phase I and II enzymes involved in the metabolism of carcinogens are polymorphic in genotypes. This case-control study focused on the interactions between oral cancer risk factors and genetic polymorphisms of cytochrome P-450 (CYP) 2E1 and glutathione S-transferase (GST) M1 and GSTT1. A total of 41 male oral ...

Abstract β-lactamases are a diverse class of enzymes produced by bacteria that present major cause for resistance to β-lactams. In this study we analysed 159 fecal samples from dairy cows, the presence presumptive ESBL, AmpC, and carbapenemase-producing E. coli . Phylotyping was done using Clermont phylo-typing method, targeting arpA, ChuA, YjaA genes, along with DNA fragment TspE4.C2. Convetio...

The balance between phosphoinositides distributed at specific sites in the plasma membrane causes polarized actin polymerization. Oncogenic transformations affect this by regulating phosphoinositide 3-kinase (PI3K) and phosphatase tensin homolog deleted on chromosome 10 (PTEN), causing metastatic behavior cancer cells. Here, we show that PTEN tumor suppressor gene is required for epithelial cel...

LetX be an algebraicK3 surface. Fix an ample divisorH onX ,L ∈ Pic(X) and c2 ∈ Z. Let MH(r;L, c2) be the moduli space of rank r, H-stable vector bundles E over X with det(E) = L and c2(E) = c2. The goal of this paper is to determine invariants (r; c1, c2) for which MH(r;L, c2) is birational to some Hilbert scheme Hilb(X).

Microtext can be considered one form of micro-messaging which can include non-digital communications which have been digitized. We present our experiences and some results analyzing micro-messages in both military command and control (C2) and more general “C2-Lite” domains in order to predict other information such as the performance of a team, the topics of discussion, or the spread of ideas. ...

An approach to the generation of future adaptive mission-oriented command and control architectures is presented that uses “command and control capabilities” concept both for missions and C2 systems. The concept is modeled and formulated so that both missions and C2 systems can be normatively described by it: on the one hand, missions require the military has specific C2 capabilities and on the...

Let C1, C2 be Cantor sets embedded in the real line, and let τ1, τ2 be their respective thicknesses. If τ1τ2 > 1, then it is well known that the difference set C1 − C2 is a disjoint union of closed intervals. B. Williams showed that for some t ∈ int(C1−C2), it may be that C1∩ (C2 + t) is as small as a single point. However, the author previously showed that generically, the other extreme is tru...

Toll-interacting protein (Tollip) is a critical regulator of TOLL- like receptor (TLR)-signaling pathway. It predominantly associated with TLR2 and TLR4 during acute inflammatory conditions inhibits the TLR-mediated nuclear factor-kappa activation by suppressing autophosphorylation interleukin-1 receptor-associated kinase its activity. This article describes Tollip Labeo rohita (LrTollip), high...