نتایج جستجو برای: calcitonin
تعداد نتایج: 6447 فیلتر نتایج به سال:
Sixteen consecutive patients in one unit were studied during long-term treatment of Paget's disease of bone with salmon calcitonin. Eleven patients developed detectable antibody titres at some time during treatment. In one patient with a high antibody titre evidence of resistance to treatment emerged two years after the development of antibodies, but no other patient showed evidence of resistan...
1. The effects on renal electrolyte excretion of human and salmon synthetic calcitonins were studied in the rat. 2. As little as 50 ng of salmon calcitonin produced an increase in sodium excretion, but human calcitonin in doses up to 15 pg had only a slight effect. 3. Small doses of both hormones decreased urinary calcium and magnesium. Larger doses of salmon calcitonin produced less depression...
The primary step of calcitonin biosynthesis was studied in a normal organ: chicken ultimobranchial gland, a tissue particularly rich in calcitonin secretory cells. Poly(A)-rich RNA was extracted and purified from ultimobranchial organs and translated in a reticulocyte lysate in the presence of labelled methionine. Polyacrylamide gel electrophoresis of specific immunoprecipitates revealed a majo...
A study of 26 men with bronchogenic cancer demonstrated high serum calcitonin levels in 62 percent (16). Levels were particularly high in patients with small-cell cancer and adenocarcinoma. Two varieties of hypercalcitonemia have been encountered: (1) ectopic hypercalcitonemia, in which the hormone is secreted by the tumor, and (2) thyroidal hypercalcitonemia, in which the high values emanate f...
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