Vegetables generally contain more or less oxalic acid, which is produced by metabolism in cytoplasm.12 Most of the oxalic acid is fixed as calcium oxalate to protect protoplasm from its toxic action.3 Vegetables containing a considerable quantity of oxalic acid are usually boiled before being cooked to remove any harshness.4 The oxalic acid contained in food is determined by the KMnO4 titration...

Calcium oxalate druses were isolated from the stems and leaves of six Pereskioideae family members and investigated by infrared spectroscopy, showing that in all samples the biomineral was present in the form of whewellite, CaC2O4 x H2O. As Pereskia is thought to represent the "ancestral" condition of the leafless stem-succulent cacti, these results suggest that the biomineralization of calcium...

Citation: Steiger S, Grill JF, Ma Q, Bäuerle T, Jordan J, Smolle M, Böhland C, Lech M and Anders H-J (2018) Anti-Transforming Growth Factor β IgG Elicits a Dual Effect on Calcium Oxalate Crystallization and Progressive NephrocalcinosisRelated Chronic Kidney Disease. Front. Immunol. 9:619. doi: 10.3389/fimmu.2018.00619 anti-Transforming growth Factor β igg elicits a Dual effect on calcium Oxalat...

Nephrolithiasis remains a major health problem in Western countries. Seventy to 80% of kidney stones are composed of calcium oxalate, and small changes in urinary oxalate affect risk of kidney stone formation. Intestinal oxalate secretion mediated by the anion exchanger SLC26A6 plays an essential role in preventing hyperoxaluria and calcium oxalate nephrolithiasis, indicating that understanding...

Tamm-Horsfall glycoprotein (THP) from healthy probands inhibits the precipitation of calcium oxalate, whereas THP from individuals who repeatedly develop calcium oxalate stones has no effect or even promotes precipitation. Using Fourier-transform infrared spectroscopy, we found a structural differentiation between these functionally different THPs: a decisive difference in sialic acid content. ...

We present an adult autopsy case of primary hyperoxaluria type 1. Diagnosis was established with skin biopsy and subsequent genetic analysis one month prior to death. At autopsy, calcium oxalate crystals refringent to polarized light were found systemically. Interestingly, however, calcium oxalate crystals were not identified in the bone. Additionally, we have included a review of the literatur...

Thirty-six patients with recurrent calcium oxalate nephrolithiasis were selected from the stone clinic. Fourteen were normocalcemic and had normal daily urinary calcium excretion. Among 22 patients with idiopathic hypercalciuria, 10 received thiazide diuretics for the prevention of new stone formation. Single-voided urine samples were collected at the outpatient clinic and 24-hour urine at the ...

PURPOSE Exposure to the microgravity environment of space increases the risk of kidney stone formation, particularly for calcium oxalate and uric acid stones. This study was performed to evaluate the efficacy of potassium alkali as potassium-magnesium citrate in reducing renal stone risk and bone turnover. MATERIALS AND METHODS This study was performed as a double-blind, placebo controlled tr...

This study examined the calcium transport properties of two subcellular fractions of bovine aorta obtained by differential centrifugation. The vesicular fraction had a high-affinity (Km = 1.05 X 10(-6)M) calcium transport mechanism which could be potentiated by using the calcium-precipitating anion, oxalate. The mitochondria-enriched fraction's calcium transport system had a lower affinity for ...

The aim of this study was to examine the effect of Takusha (Alismatis rhizoma), a Kampou medicine, on the formation, growth and aggregation of calcium oxalate (CaOx) crystals by a seed crystal system, an undiluted urine system and a continuous flow crystallizer system. In the seed crystal method using a metastable solution, the inhibitory effect on aggregation and growth of CaOx crystals was ca...