Rats given 4 mg. fluoride/kg./day for eight days excreted more calcium and phosphorus and retained less than the controls. In bone ash from rats given different fluoride doses for 40 days the calcium and phosphorus were maximal after a total dose of about 250 ,tg. fluoride/rat, but fell to subnormal levels after higher doses. The calcium and phosphorus levels in bone ash from rats given 750 pg....

: The mechanisms of the formation and transformation of calcium carbonates and the inhibition by the phosphorus containing compounds were studied. Supersaturated solutions form the unstable polymorph, amorphous calcium carbonate, at first, followed by the transformation to the metastable polymorph which finally transforms to stable form, calcite. Transformation proceeds by a mechanism of recrys...

Large amounts of calcium and phosphorus have been found by electron-microprobe analysis in the dense bodies of frozen-dried, human platelets. The calcium and phosphorus occurred in a fixed ratio that was similar to that in dicalcium ATP. No other elements were detectable except chlorine. Minute, electron-dense disks were found in the surface membranes of glutaraldehyde-fixed platelets, and are ...

The effects of two dietary proteins on α-amino acids, calcium and phosphorus concentrations in plasma, stomach and intestine were investigated in rats trained to consume, in a single two-hour daily meal, diets containing α-lactalbumin (α-la) or whey protein concentrate (WPC) for two weeks. The results indicated that the concentrations of calcium and phosphorus in the gastrointestinal tract and ...

To assess the significance of various maternal and neonatal factors in the aetiology of neonatal tetany we have investigated the serum calcium, phosphorus, magnesium, and heat-labile alkaline phosphatase of 250 mothers from three ethnic groups at several stages of pregnancy and the serum calcium, phosphorus, and magnesium of many of their infants. Subclinical hypocalcaemia was found to be much ...

w1as 13.8 mgiml. per cetit. T'lhe blood phosphorus, however, as only 1.8 mgm. per cenit., so that the ratio between calcium anid phosphorus, stea(l of being thc niormiial two to one, wkas eight to one. WVhile it is more usual to nd both the bloo(d calcium and phosphorus lower than niormal, it is this alteration the calcium-phosphorl-ls ratio that is typical of rachitic bloo(d clhemistry. -In sp...

Vitamin D is an important physiologic regulator of bone and mineral metabolism. In chronic kidney disease, reduced renal production of calcitriol contributes to secondary hyperparathyroidism (SHPT). Consequently, supplementation with vitamin D sterols is an important treatment for SHPT and its associated mineral and bone disorders. However, doses of vitamin D sterols required to suppress parath...

The effects of parathyroid hormone on bone and kidney have been well documented (1). It has not been settled, however, whether the hormone exerts similar actions in the rachitic animal. Ras-mussen and associates have found that parathy-roid hormone lowers the serum phosphorus in the vitamin D-depleted rat (2). Harrison and Har-rison, however, observed that vitamin D-depleted rats did not respon...

BROOKFIELD [1933] showed that in the serum of the rabbit there was an inverse relationship between calcium and magnesium, a direct relationship between magnesium and inorganic phosphorus and an inverse relationship between calcium and inorganic phosphorus, the latter of which had been previously observed by Dupre and Semeonoff [1931] and Bourne and Campbell [1932]. The rises and falls in the co...