Pressure perturbation differential scanning calorimetry was used to determine thermal expansion coefficients and thus temperature-induced volume changes of DNA duplexes differing in their GC/AT content. It was shown that the temperature-induced unfolding of the DNA duplexes proceeds with a significant increase of the thermal expansion coefficient and the partial volume of the DNA. Unusually, la...

We study the phase behavior of saturated lipids as a function of temperature and tail length for two coarse-grained models: the soft-repulsive model typically employed with dissipative particle dynamics (DPD) and the MARTINI model. We characterize the simulated transitions through changes in structural properties, and we introduce a computational method to monitor changes in enthalpy, as is don...

Proteins are essential for life and as such have been deemed useful as therapeutic agents. However, the complexities that make proteins important for biological processes can also make their behaviour complicated. Such behaviour can make production, processing and formulation of protein pharmaceuticals problematic. A therapeutic protein test system has been examined using infrared spectroscopy ...

The reduction of tungsten hexachloride with lead powder was investigated by differential scanning calorimetry (DSC) combined with X-ray diffraction (XRD) studies. Intermediate compounds along the way of the reduction of W6+ to W2+ were detected, prepared by solid-state synthesis, and structurally characterized by X-ray diffraction techniques. Five new compounds, namely Pb0.5WCl6, PbW2Cl10, Pb1....

Interaction between aspartic acid and D-glucose, D-galactose, and D-fructose has been studied by isothermal titration calorimetry, calorimetry of dissolution, and densimetry. It has been found that D-glucose and D-fructose form thermodynamically stable associates with aspartic acid, in contrast to D-galactose. The selectivity in the interaction of aspartic acid with monosaccharides is affected ...

Low-temperature heat capacities from 5 to 350 K by adiabatic calorimetry and high-temperature enthalpy increments above 450 K by drop calorimetry of high-purity Sr(OH), and /I-Ba(OH), have been measured. From the results, smoothed thermochemical and thermophysical functions of the two compounds have been tabulated at selected temperatures.

AIM The purpose of this review was to assess existing evidence on the effects of chronic dietary macronutrient composition on substrate oxidation during a fasted state in healthy and overweight subjects. METHODS A systematic review of studies was conducted across five databases. Studies were included if they were English language studies of human adults, ≥19 years, used indirect calorimetry (...

A serious limitation in the study of protein folding reactions resides in the lack of experimental methods to measure the absolute height of the free energy barrier. This is particularly unfortunate given that if folding barriers are small, as theory predicts, it might be possible to resolve folding mechanisms directly. Here we explore the performance of a recently developed method to extract f...