BACKGROUND Our study objectives were to evaluate the medical economics of cervical cancer prevention and thereby contribute to cancer care policy decisions in Japan. METHODS Model creation: we created presence- absence models for prevention by designating human papillomavirus (HPV) vaccination for primary prevention of cervical cancer. Cost classification and cost estimates: we divided the co...

cancer has emerged as a major public health concern owing to its magnitude, worldwide distribution, impact on the quality of life, financial burden on the patient / family / society / health care delivery system, and associated mortality. findings of a study have shown that approximately 19% of all types of cancers have been attributed to the environmental factor. almost 900 potential carcinoge...

Introduction. Breast cancer is a malignant tumor that grows in breast tissue can come from components such as fat tissue, blood vessels. Early detection one of the prevention efforts help reduce incidence cancer. There are three ways to prevent including primary prevention, secondary and tertiary preventionMethod. This study uses descriptive type research with cross-sectional approach. The popu...

The aim of cancer prevention is to develop methods, plans or policy for interventions that will benefit the population, as well as develop systems for monitoring and evaluating these interventions in the future. The purpose of interventions is to reduce the incidence, morbidity, mortality rates of cancer and cost of cancer management. Because the modes of interventions that will be employed inv...

This article investigates maximum likelihood estimation with saturated and unsaturated models for correlated exchangeable binary data, when a sample of independent clusters of varying sizes is available. We discuss various parameterizations of these models, and propose using the EM algorithm to obtain maximum likelihood estimates. The methodology is illustrated by applications to a study of fam...

Cervical cancer remains the second commonest cancer among women worldwide, and more than 85% of the global burden of this disease occurs in the developing world. HIV-infected women have a higher likelihood of developing persistent high-risk human papillomavirus (HPV) infection, precancer, and invasive cervical cancer than seronegative women. Although highly effective primary and secondary preve...

BACKGROUND There is a common belief that most cancer prevention trials should be restricted to high-risk subjects in order to increase statistical power. This strategy is appropriate if the ultimate target population is subjects at the same high-risk. However if the target population is the general population, three assumptions may underlie the decision to enroll high-risk subject instead of av...

background: chemokine receptors have been shown to play an important role in the development and metastatic spread of various malignancies. in this study, the gene expression profile of some key chemokine receptors involved in metastasis has been investigated in esophageal and breast cancer cell lines.   methods: in a descriptive study, gene expression profile of ccr1, ccr6, ccr7, ccr9, cxcr1, ...

background: oral cancer has emerged as a significant cause of global public health concern. if a cancerous lesion is diagnosed in primary stages, the survival rate would be higher. thus, the aim of this study was to evaluate knowledge, attitude and practice of general dentist regarding oral cancer in sari, iran. methods: this cross sectional analytical study was performed on general dentists of...

250-words max è stato accorciato per rientrare nelle linee guida) 248 At several recent, internationally attended scientific meetings, including the American Association for Cancer Research (AACR)'s "Shaping the Future of Cancer Prevention: A Roadmap for Integrative Cancer Science and Public Health" summit in Leesburg (VA) and the AACR Annual Meeting in New Orleans, the focus on cancer preventi...