introduction candidiasis as an opportunistic infection is created by some species of candida. here the role of candida albicans is more noticeable than other species. candida can cause an extended spectrum of symptoms. due to the increasing consumption of immunosuppressants including corticosteroids and diseases like diabetes, candidiasis has drawn more attention than before. methods considerin...

Allergic Bronchopulmonary Mycosis (ABPM) is an exagregated immunologic response to fungal colonization in the lower airways. It may cause by many kinds of fungal, but Aspergillus fumigatus is the most common cause of ABPM, although other Aspergillus and other fungal organisms, like Candida albicans, have been implicated. Aspergllus fumigatus and Candida albicans may be found as outdoor and indo...

Introduction: Candida albicans is the most common oral fungus associated with oral candidial infections. Various antifungal agents are in use and the search is on for more agents showing anti candidial properties. Ganodermalucidum has been in use in Traditional Chinese Medicine for years. Literature supports the use of this Ganodermalucidum as a medicinal mushroom for its antimicrobial, antivir...

In this study, we evaluated the interactions between Candida albicans, Candida krusei and Candida glabrata in mixed infections. Initially, these interactions were studied in biofilms formed in vitro. CFU/mL values of C. albicans were lower in mixed biofilms when compared to the single biofilms, verifying 77% and 89% of C. albicans reduction when this species was associated with C. glabrata and ...

One of the mechanisms of Candida albicans resistance to azole drugs used in antifungal therapy relies on increased expression and presence of point mutations in the ERG11 gene that encodes sterol 14α demethylase (14DM), an enzyme which is the primary target for the azole class of antifungals. The aim of the study was to analyze nucleotide substitutions in the Candida albicans ERG11 gene of azol...

In-vitro studies on the efficacy of crude extracts of Aloe secundiflora on Candida albicans was conducted. Five mature leaves of Aloe secundiflora were collected and the crude extract was prepared, then autoclaved. The extract was then tested on Candida albicans grown on solid media. The results from these studies revealed complete inhibition of Candida albicans growth caused by Aloe secundiflo...

The aim of this study was to evaluate the use of one of the molecular typing methods such as PCR (polymerase chain reaction) following by RFLP (restriction fragment length polymorphism) analysis in the identification of Candida species and then to differentiate the identified azole susceptible and resistant Candida albicans strains by using AP-PCR (arbitrarily primed-polymerase chain reaction)....

Background: Due to the predisposing conditions in patients with cystic fibrosis (CF) caused by defective mucociliary clearance facilitating colonization and invasion with Candida species has dramatically increased. Traditional methods for identifying problems are imminent and time-consuming. Therefore, molecular techniques utilizing amplification of target DNA provide quick and precise methods ...

A study was conducted to determine the effect of the Candida albicans mannoprotein on Phagocytic activity, antibody production, serum gammaglobuline percentage and lymphocyte transformation index after vaccination with hepatitis B surface (HBs) antigen. It can be concluded that Mannoprotein isolated from Candida albicans cell wall are an important immunomodulatorts in the development of immune ...