Klebsiella pneumoniae carbapenemases (KPCs) are plasmid encoded carbapenem hydrolyzing enzymes which have the potential to spread widely through gene transfer. The instability of upstream region of blaKPC accelerates emergence of different isoforms. Routine antibiotic susceptibility testing failed to detect KPC producers and some commercial kits have been launched for early identification of KP...

Gram-negative multidrug-resistant organisms (GN-MDRO) producing β-lactamases (ESBL, plasmid-mediated AmpC β-lactamases and carbapenemases) are increasingly reported throughout Asia. The aim of this surveillance study was to determine the rate of bacterial colonization in patients from two hospitals in the Mongolian capital Ulaanbaatar. Rectal swabs were obtained from patients referred to the Na...

In their excellent review of the classification of carbapenemhydrolyzing metallo-b-lactamases, Rasmussen and Bush (6) proposed that such enzymes produced by Bacteroides fragilis should be assigned to a new functional subgroup, 3a. The characteristics of b-lactamases from three B. fragilis strains were cited and included those from B. fragilis QMCN3 and B. fragilis QMCN4 (7, 8). To avoid confusi...