نتایج جستجو برای: carbon and reduced from 006 cms to 0014 cms
تعداد نتایج: 18937664 فیلتر نتایج به سال:
Intravenous colistin methanesulfonate (CMS) is increasingly the last line of defense for multidrug-resistant gram-negative bacteria and is now being used as “salvage” therapy in critically ill patients (1, 7, 9, 11). CMS is converted in vivo to colistin, and these two entities have substantially different pharmacokinetics, antibacterial activities, and toxicities (7), and therefore it is import...
this thesis is an evaluation of poetry of sylvia plath (1932- 1963) and forough farrokhzad (1935-1967) using feminist approach and finds the positive concepts of hope, reason and strength through feminine images in their poetry. plath and farrokhzad are from different cultures and different countries but they share the same concepts and themes in their poetry. by applying feminist theory to the...
Congenital myasthenic syndromes (CMS) are rare and heterogeneous genetic diseases characterized by compromised neuromuscular transmission and clinical features of fatigable weakness; age at onset, presenting symptoms, distribution of weakness, and response to treatment differ depending on the underlying molecular defect. Mutations in one of the multiple genes, encoding proteins expressed at the...
This document gives a comprehensive overview of the data grid system that CMS intends to operate around December 2003. This CMS data grid system will support both CMS production and analysis and will seamlessly tie together resources at CERN and at international CMS regional centers. This document focuses on the relation between the CMS software components and the grid software components opera...
INTRODUCTION Fever can increase the susceptibility to supraventricular and ventricular arrhythmias, in which sodium channel dysfunction has been implicated. Whether fever influences the efficacy of sodium channel blocking drugs is unknown. The current study was designed to investigate the temperature dependent effects of distinct sodium channel blocking drugs on the sodium currents in human ind...
Extracellular signal regulated kinase½ (ERK1/2) signaling is critical to endothelin-1 (ET-1)-induced cardiomyocyte hypertrophy. This study was to investigate ERK1/2 signaling and hypertrophic response to ET-1 stimulation in cardiomyocytes (CMs) from spontaneous hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY). Primary neonatal SHR and WKY CMs were exposed to ET-1 for up to 24 hr...
The objectives of the study were to detect the effect of substance P receptor antagonist aprepitant on a rat model of asthma and depression. Ovalbumin (OVA)-induced asthmatic Wistar rats were exposed to a chronic mild stress (CMS) procedure which was usually used to induce depression in animals. Simultaneously with the CMS, two groups of the rats were respectively given either aprepitant or sla...
BACKGROUND Human embryonic stem cells (hESCs) derived from blastocysts can propagate indefinitely in culture while maintaining pluripotency, including the ability to differentiate into cardiomyocytes (CMs); therefore, hESCs may provide an unlimited source of human CMs for cell-based therapies. Although CMs can be derived from hESCs ex vivo, it remains uncertain whether a functional syncytium ca...
ارزیابی پاسخ لرزه ای سازه ها اغلب مستلزم انتخاب یک مجموعه شتابنگاشت زمین لرزه می باشد. رویکرد متداول جهت انتخاب شتاب نگاشت ها، تطابق میانگین مجموعه رکوردهای منتخب با طیف هدف در یک محدوده فرکانسی مشخص می باشد. طیف هدف توصیه شده توسط بسیاری از آیین نامه ها، طیف یکنواخت خطر (uhs) است که محققین بسیاری بر محافظه کارانه بودن آن تاکید کرده اند. اخیرا طیف هدف مدرن تری موسوم به طیف میانگین شرطی (cms) ار...
Cardiovascular disease is a leading cause of morbidity in rheumatoid arthritis (RA) patients. This study aimed to generate and characterise cardiomyocytes from induced pluripotent stem cells (iPSCs) of RA patients. Fibroblast-like synoviocytes (FLSs) from patients with RA and osteoarthritis (OA) were successfully reprogrammed into RA-iPSCs and OA-iPSCs, respectively. The pluripotency of iPSCs w...
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