1. A Sepharose-(glutathione-2-pyridyl disulphide) conjugate has been prepared. 2. Its use in a new type of chromatography, covalent chromatography by thiol-disulphide interchange, is described. 3. With this technique, papain containing 1 intact catalytic site [thiol with high reactivity towards 2,2'-dipyridyl disulphide (2-Py-S-S-2-Py) at pH4] per mol of protein is readily prepared both from dr...

Disulphide bonds between cysteine residues in proteins play a key role in protein folding, stability, and function. Loss of a disulphide bond is often associated with functional differentiation of the protein. The evolution of disulphide bonds is still actively debated; analysis of naturally occurring variants can promote understanding of the protein evolutionary process. One of the disulphide ...

Organohalide perovskite with a variety of surface structures and morphologies have shown promising potential owing to the choice type heterostructure dependent stability. We systematically investigate discuss impact 2-dimensional molybdenum-disulphide (MoS2), molybdenum-diselenide (MoSe2), tungsten-disulphide (WS2), tungsten-diselenide (WSe2), boron-nitiride (BN) graphene monolayers on bandgap ...

Biofilm-related infections and contamination of biomaterials are major problems in the clinic. These contaminations frequently caused by Staphylococcus aureus a pressing issue for implantable devices, catheters, contact lenses, prostheses, wound dressings. Strategies to decrease biofilm related vital success biomaterials. In this context, hyaluronic acid (HA), naturally derived carbohydrate pol...