MITOCHONDRIA PRESENT TWO KEY ROLES ON CELLULAR FUNCTIONING: (i) cell metabolism, being the main cellular source of energy and (ii) modulation of cell death, by mitochondrial membrane permeabilization. Carbon monoxide (CO) is an endogenously produced gaseoustransmitter, which presents several biological functions and is involved in maintaining cell homeostasis and cytoprotection. Herein, mitocho...

This review focuses on how microbes live on CO as a sole source of carbon and energy and with CO by generating carbon monoxide as a metabolic intermediate. The use of CO is a property of organisms that use the Wood-L jungdahl pathway of autotrophic growth. The review discusses when CO metabolism originated, when and how it was discovered, and what properties of CO are ideal for microbial growth...

Three years of global carbon monoxide from SCIAMACHY: comparison with MOPITT and first results related to the detection of enhanced CO over cities M. Buchwitz, I. Khlystova, H. Bovensmann, and J. P. Burrows Institute of Environmental Physics (IUP), University of Bremen FB1, Bremen, Germany Received: 7 December 2006 – Accepted: 8 January 2007 – Published: 11 January 2007 Correspondence to: M. Bu...

Sir, The recent review of carbon monoxide poisoning by Balzan et al' provided helpful advice about this sometimes difficult diagnosis. We would, however, hesitate to follow the recommendations made about the treatment of CO poisoning. Their assessment of the benefit of hyperbaric oxygen (HBO) does not appear to be based on the presented evidence and the potential complications of transporting c...

The largest occurrence of carbon monoxide poisoning in Britain demonstrates the potential for mass accidental poisoning. It emphasises the need for strict public health controls and the importance of good liaison between emergency services to ensure that such events are quickly recognised and that the necessary resources are organised.

The water-gas shift (WGS) reaction (where carbon monoxide plus water yields dihydrogen and carbon dioxide) is an essential process for hydrogen generation and carbon monoxide removal in various energy-related chemical operations. This equilibrium-limited reaction is favored at a low working temperature. Potential application in fuel cells also requires a WGS catalyst to be highly active, stable...

Carbon monoxide is one of the most common toxins encountered in work settings, the gas being emitted in situations where there is incomplete combustion of carbon-containing substances. Its acute and chronic health effects have been well-documented. While identification of dangerous situations and evaluation of control measures are conducted by environmental monitoring, the body burden due to in...

A novel spectrophotometric method for the estimation of carbon monoxide at levels from 2 to 250 ppm is presented. The method is empirical and based on formation of a carbonyl complex of ruthenium(II) octaethylporphyrin and measurement of the difference in absorbance at 393.5 nm between this complex and the porphyrin reagent. Oxygen and nitrogen do not interfere and up to 300 ppm of sulphur diox...

Carbon Monoxide (CO) is the most abundant air pollutant gas and accumulates rapidly to dangerous concentrations even in areas that seem to be well ventilated. Carbon monoxide detectors/alarm systems exist but people who are old, hearing impaired, partially sighted or heavy sleepers may not get the warning or find it difficult to wake up and get out in the event of dangerous concentration of CO ...

CO, binds to the iron atoms in hemoglobin, with an affinity 200-250 times that of oxygen, and impairs oxygen carrying capacity of the blood. Hence, CO toxicity is a situation characterized by impairment of oxygen transportation and consumption. It has been reported that 30% of such cases are not diagnosed since the signs and symptoms in CO intoxication. Definitive diagnosis of CO intoxication i...