Acute cardiac tamponade requires urgent diagnosis and treatment. Spontaneous hemopericardium leading to cardiac tamponade as an initial manifestation of essential thrombocythemia (ET) has never been reported in the literature. We report a case of a 72-year-old Caucasian female who presented with spontaneous hemopericardium and tamponade requiring emergent pericardiocentesis. The patient was sub...

Sudden cardiac death, also known as primary cardiac arrest (PCA), is a major cause of mortality among diabetic patients and typically occurs in the setting of coronary heart disease. Because it can occur as the first clinical manifestation of coronary heart disease, identifying diabetic patients at risk of PCA remains challenging. Interrelated sequelae of diabetes, including QT prolongation and...

Sudden unexpected cardiac death is the most devastating feature of the natural history of hype~rophic cardiomyopathy and in many patients is the first clinical manifestation of the disease (1-7). Although left ventricular hypertrophy appears to be an important determinant of many functional features of hypertrophic cardiomyopathy, the reialion between the magnitude of hypertrophy and the occurr...

Mitochondrial disease refers to a heterogenous group of genetic disorders that result from dysfunction of the final common pathway of energy metabolism. Mitochondrial DNA mutations affect key components of the respiratory chain and account for the majority of mitochondrial disease in adults. Owing to critical dependence of the heart on oxidative metabolism, cardiac involvement in mitochondrial ...

Background Cardiovascular sequelae represent a leading cause of mortality in Fabry disease. Early detection of cardiac involvement is therefore a subject of considerable interest. Low native T1 values have been shown to be associated with echocardiographic markers of early systolic and diastolic dysfunction, even in those without left ventricular hypertrophy (LVH), and conceptually could be use...

Hypertrophic cardiomyopathy (HCM) is characterized by gross cardiac and myocyte hypertrophy, myocyte disarray, and interstitial fibrosis. This condition is relatively common, with a prevalence of about 1:500 in the general population. Most patients with HCM are either asymptomatic or have only minimal symptoms. In general, HCM is a relatively benign disease with an annual mortality rate of slig...

Sudden cardiac arrest is the main manifestation of ischemic heart diseases, which is the leading cause of death worldwide. Each year an estimated 300,000 people suffer from cardiac arrest in the United States, with a variable incidence ranging from 36/100,000 to 128/100,000. Approximately 7.9% of cardiac arrest victims survive to hospital discharge in the United States, whereas fewer than half ...

P effusion is a common manifestation of hypothyroidism, observed in approximately 1/3 of patients without replacement therapy.1 In hypopituitarism, pericardial effusion is usually due to hypothyroidism, however, cardiac tamponade is a very rare complication of both hypothyroidism and adrenal insufficiency.2-4 Herein, we report a case of hypopituitarism with myxedema and pericardial effusion, in...

Point-of-care ultrasound of echocardiographic is capable identifying the precise causes hemodynamic disorder in patients with sepsis especially septic shock [1]. Patients demonstrate complex alterations their circulation, including changes preload and afterload right ventricle dysfunction [2]. Based on systemic inflammation it can also cause a significant proportion acute lung injury, as most c...

Br J Cardiol 2009;16:175–80 T relationship between cardiac and gastrointestinal disease is widely regarded as being a complex one – disorders of the two systems commonly co-exist, and the symptoms of angina pectoris are notoriously difficult to differentiate from gastro-oesophageal problems. In addition, it has commonly been observed that patients suffering with gastrointestinal disturbance suf...