Abstract Background National essential medicines lists are used to guide medicine reimbursement and public sector procurement for many countries therefore listings may impact health outcomes. Methods Countries’ national were scored on whether they listed proven ischemic heart disease, cerebrovascular disease hypertensive disease. In this cross sectional study linear regression was measure the a...

orf is a mucocutaneous disease that occurs when non-intact skin comes into contact with contaminated sheep saliva. the lesions may complicate to lymphangitis or secondary bacterial infection, but systemic complications such as erythema multiforme, maculopapular rash, and generalized lymphadenopathy are rare. in this paper, we present two cases of erythema multiforme following orf disease.

The past decade has seen tremendous advances in our understanding of the genetic factors influencing response to a variety of drugs, including those targeted at treatment of cardiovascular diseases. In the case of clopidogrel, warfarin, and statins, the literature has become sufficiently strong that guidelines are now available describing the use of genetic information to guide treatment with t...

Cardiovascular diseases are among the leading causes of morbidity and mortality in the developed world despite advances in cardiac care over the last few decades. Although most of these advances in cardiovascular medicine have been made through trials of therapies on a population scale, the success of such therapies in a patient often is dependent on particular aspects of each individual. In th...

Aspirin was first synthesised 100 years ago and its preparation and marketing is generally reckoned to have been the foundation of the pharmaceutical industry. For most of the time since then it has been used for the reliefofpain and fever. The modern phase of aspirin use commenced with the reporting in 1974 of a randomised controlled trial in the secondary prevention of death by low-dose aspir...

Ischemic heart disease related myocardial infarction (MI) remains the leading cause of mortality in western countries and increasingly in the rest of the world. However, there are no therapies currently available to directly treat MI-induced death of cardiomyocytes to improve cardiac function in the infarct zone.Cardiac tissue regeneration in the infarct zone using stem cells is a promising app...